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Can norovirus infection increase CRP levels?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I had a CRP (C-reactive protein) of 100, which is a sign of bacterial infection, but the test showed norovirus which should give a CRP of below 5 mg/dL. What could be the reason for my extreme illness and high CRP? Is this a sign of an underlying illness, or is it a sign of an overactive immune response? My sister has Sarcodiosis and I have asthma and allergies.

Please help.

Answered by Dr. Ghulam Fareed

Education:

MBBS

Professional Bio:

Dr. Ghulam Fareed is a skilled medical gastroenterologist with expertise in diagnosing and treating digestive system disorders. He specializes in managing conditions like acid reflux, hepatitis, ulcers, and inflammatory bowel disease. With years of clinical experience, he focuses on accurate evaluation, advanced endoscopic procedures, and long-term gastrointestinal health management.      

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

C-reactive protein (CRP) is the marker of inflammation, not bacterial infection.

Yes, you are right, it will be high in bacterial infections because all infections can cause inflammation, but in non-bacterial infections like viral or fungal infections, it will go up too. It can go up with non-infective inflammation conditions like severe asthma, allergies, rheumatoid arthritis, and ulcerative colitis.

In your case, three possibilities are:

  1. Norovirus itself.

  2. Superimposed bacterial Infection (there is a possibility, but I do not know your history, so cannot say it for sure).

  3. Non-infective inflammation, if your asthma or allergies are bad these days.

I hope this has helped you.

Please feel free to reach me again, in case of further queries.

Thank you.

Medically reviewed by iCliniq medical review team
Published At January 26, 2025
Reviewed At January 26, 2025

Education:

MBBS

Professional Bio:

Dr. Ghulam Fareed is a skilled medical gastroenterologist with expertise in diagnosing and treating digestive system disorders. He specializes in managing conditions like acid reflux, hepatitis, ulcers, and inflammatory bowel disease. With years of clinical experience, he focuses on accurate evaluation, advanced endoscopic procedures, and long-term gastrointestinal health management.      

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Ghulam Fareed is a skilled medical gastroenterologist with expertise in diagnosing and treating digestive system disorders. He specializes in managing conditions like acid reflux, hepatitis, ulcers, and inflammatory bowel disease. With years of clinical experience, he focuses on accurate evaluation, advanced endoscopic procedures, and long-term gastrointestinal health management.      

This doctor is not available for online consultations on the platform anymore.

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