HomeAnswersInternal MedicineomeprazoleDoes long-term use of Omeprazole cause hypomagnesemia?

Does Omeprazole cause hypomagnesemia?

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Published At November 12, 2022
Reviewed AtOctober 9, 2023

Patient's Query

Hello doctor,

Two weeks ago, I felt nauseous after meals with excessive burping. I also have a history of more than one type of arrhythmia: heavy pounding for a week, continuous, slightly misaligned heart rhythm, supraventricular tachycardia, and dizziness. So I visited a doctor who suspected a stomach ulcer and was advised to take tablet Omeprazole. Unfortunately, I read that Omeprazole causes hypomagnesemia. What is the time scale for developing hypomagnesemia? Am I at any risk if I do not take these pills long-term?

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Omeprazole causes diarrhea, which may cause hypomagnesemia, but you should not worry as it occurs only in 2 % and causes insignificant hypomagnesemia.

Hypomagnesemia sometimes is severe and may cause life-threatening arrhythmia. Hence, serum magnesium should be checked, and replacement could be started if serum magnesium is low. It is common to be associated with low calcium levels as well.

Please send me your electrocardiogram (ECG) report for further interpretation.

I hope this helps.

Thank you and take care.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Mahmoud Ahmed Abdelrahman Abouibrahim
Dr. Mahmoud Ahmed Abdelrahman Abouibrahim

Internal Medicine

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