Q. Does Omeprazole cause hypomagnesemia?

Answered by
Dr. Mahmoud Ahmed Abdelrahman Abouibrahim
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 12, 2022

Hello doctor,

Two weeks ago, I felt nauseous after meals with excessive burping. I also have a history of more than one type of arrhythmia: heavy pounding for a week, continuous, slightly misaligned heart rhythm, supraventricular tachycardia, and dizziness. So I visited a doctor who suspected a stomach ulcer and was advised to take tablet Omeprazole. Unfortunately, I read that Omeprazole causes hypomagnesemia. What is the time scale for developing hypomagnesemia? Am I at any risk if I do not take these pills long-term?



Welcome to

I read your query and can understand your concern.

Omeprazole causes diarrhea, which may cause hypomagnesemia, but you should not worry as it occurs only in 2 % and causes insignificant hypomagnesemia.

Hypomagnesemia sometimes is severe and may cause life-threatening arrhythmia. Hence, serum magnesium should be checked, and replacement could be started if serum magnesium is low. It is common to be associated with low calcium levels as well.

Please send me your electrocardiogram (ECG) report for further interpretation.

I hope this helps.

Thank you and take care.

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