Common "Pai Mutation" queries answered by top doctors | iCliniq
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Pai Mutation

Gene mutations that cause plasminogen activator inhibitor 1(PAI-1) deficiency are known as PAI mutations. PAI-1 is a body protein that is essential for normal clotting of the blood. PAI mutation leads to the deficiency of the PAI-1 protein. As a result, the person with the mutation has abnormal bleeding. It is a rare bleeding disorder in which an injury can lead to excessive and prolonged bleeding.

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Should I avoid folic acid during MTHFR pregnancy?

Query: Hello doctor, I am 5 weeks pregnant and I have MTHFR and PAI mutations. My doctor recommended me to take Folic acid. I read it should be avoided during MTHFR pregnancies. Along with that I am on Prozac and Euthyrox. What do you think? What should I do? Please help.  Read Full »

Dr. Sanjay Kumar Bhattacharyya

Dr. Sanjay Kumar Bhattacharyya

Answer: Hi, Welcome to icliniq.com. Truly speaking, MTHFR - methylene tetrahydrofolate reductase mutations are widely spread and all most one half of the population is having or carrying these mutations by different extent. By different extent, I mean to say, various levels of affection or involvement tha...  Read Full »

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