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HomeAnswersNeurologyphenytoinCan Eptoin cause reduced WBC count if taken during fever?

Fever with low WBC count. Could Eptoin be the cause?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

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Published At December 20, 2018
Reviewed AtSeptember 14, 2023

Patient's Query

Hello doctor,

My niece got a fever for the past eight days. Also, low white blood cells (WBC) count. The doctors tried all the tests, antibiotics and medicines, but still, the fever is not controlled. She got fits 15 days back and the doctors prescribed Eptoin tablets. My question is whether Eptoin reduce the white blood cell counts?

Answered by Dr. Aida Abaz Quka


Welcome to icliniq.com. I understand your concern and would explain that Eptoin (Phenytoin) is a drug used to treat or prevent seizures. It does not usually affect WBC, but very rarely (like all the drugs) it can cause suppression of the blood cell formation in the bone marrow. The low WBC count can be related to different possible causes like viral disease, an autoimmune disorder, drug adverse effects, etc. A myelogram may be needed to exclude a possible hematological disorder. In the meantime, I recommend taking Eptoin, as it is well known that high fever can lead to seizures. I would also recommend taking steroids, because they can increase white blood cells (WBC) and also help fight the fever.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Aida Abaz Quka
Dr. Aida Abaz Quka


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