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Why does a 49-year-old pregnant lady have red vaginal bumps?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 49 years old and 16 weeks pregnant. I thought I had a yeast infection, so I took a Fluconazole tablet. Upon further inspection, what I have is a white discharge and itchy and red bumps inside the vagina, only on the left side. They are around the vaginal opening to the urethra. Please advise what is going on. I have only had one sexual partner.

Kindly help.

Hello,

Welcome to icliniq.com.

I can understand your concern.

Thanks for the detailed information. Here is a medically grounded and respectful response considering your pregnancy and symptoms. Based on what you have described, itchiness, white discharge, and red or itchy bumps limited to one side of the vaginal opening, here are the most likely possibilities.

  • One possibility is a recurrent or resistant yeast infection. Even though you have used Fluconazole (oral) and Miconazole (topical, such as Monistat), yeast infections in pregnancy can be persistent due to hormonal changes. Some strains of Candida are also less responsive to Fluconazole.
  • Another possibility is herpes simplex virus (HSV). The red bumps could be herpetic lesions, which often start as red, itchy areas and evolve into small blisters or ulcers. They can appear localized (for example, only on one side) and do not require multiple sexual partners to occur. HSV can remain dormant for years and reactivate due to stress or pregnancy.
  • Contact dermatitis or an allergic reaction is another consideration. You might be reacting to a product such as soap, wipes, or panty liners. This often causes localized redness, irritation, and sometimes discharge due to secondary inflammation.
  • Bacterial vaginosis or a mixed infection is also possible. A strong-smelling discharge is more typical of bacterial vaginosis, but mixed infections (yeast and bacterial vaginosis) can happen. Bacterial vaginosis is more common in pregnancy and may require a different treatment approach than what you have taken.

Here are immediate recommendations while you arrange an appointment with your obstetrician.

  • Do not take more Fluconazole. It is generally not recommended during pregnancy, especially in the first trimester, although some doctors cautiously use a single dose after that.
  • Avoid further self-treatment; topical treatments can irritate the area more if it is not a yeast infection. See your obstetrician or a gynecologist as soon as possible.
  • You need a proper pelvic examination and likely a swab test to rule out yeast, bacterial vaginosis, or herpes simplex virus.
  • Keep the area clean and dry. Use warm water only (no soap), wear loose cotton underwear, and avoid any scented products.

Concerning signs require urgent evaluation. These include painful urination, fever, increasing redness or swelling, painful or expanding bumps, or if the bumps begin to blister or ulcerate. These may indicate herpes simplex virus or another more serious infection that needs medical treatment immediately, especially during pregnancy.

I hope this helps.

Take care.

Medically reviewed byiCliniq medical review team

Published At July 14, 2025
Reviewed AtJuly 18, 2025

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