Can my allergies or asthma affect IVF or pregnancy?

Question

Hello doctor,

I am 35 years old and have been struggling with persistent sneezing, watery eyes, and nasal congestion for years. My ENT (ear, nose, and throat) diagnosed me with allergic rhinitis, which tends to worsen during spring and whenever I am exposed to dust.

Recently, I have started feeling mild sinus pressure and post-nasal drip that often triggers my asthma. I use a nasal steroid spray and take Cetirizine daily, but I have been feeling constantly drowsy and irritable.

Could long-term antihistamine use lead to hormonal changes or menstrual irregularities?
I also have endometriosis, and I read that chronic inflammation might worsen hormonal imbalance. Is that true?
We are planning for IVF (in vitro fertilization) soon, but I am worried my allergies or asthma might flare during pregnancy. Are there any allergy shots or treatments that are safe while trying to conceive?
Lastly, my husband and I are considering an air purifier. Does it actually help reduce allergy symptoms, or is it just marketing hype?
Also, are there any dietary changes that can naturally improve allergic rhinitis or asthma control?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I have read your query and can understand your concern.

From what you have shared, your symptoms and concerns are completely valid, especially since you are managing allergies, asthma, and endometriosis together while planning for IVF (in vitro fertilization). Let us address each of your worries step by step.

Using antihistamines like Cetirizine daily, at standard doses, is not known to cause hormonal changes or menstrual irregularities. Everyone’s body reacts differently, but long-term use at normal doses is generally safe. Hormonal effects are rare and not well documented unless taken in very high doses or combined with other sedating antihistamines.

Now, about the inflammation and endometriosis, you are right, chronic inflammation, such as that seen in endometriosis, can sometimes worsen hormonal imbalance. This happens because the condition is estrogen-dependent and involves ongoing immune and inflammatory activity. Managing inflammation through medication, diet, and stress control can help balance hormones naturally.

If you are already on allergy shots (immunotherapy), they can usually be continued safely during pregnancy. However, doctors do not recommend starting new allergy shots while pregnant, as the body’s reaction can be unpredictable.

Keeping asthma under control is very important for both your health and the baby’s oxygen supply. Most inhalers, nasal sprays, and common antihistamines are safe in pregnancy when prescribed by your doctor. Avoid stopping them suddenly without medical advice.

Air purifiers with HEPA (high efficiency particulate air) filters can help reduce indoor allergens like pollen, dust, and pet dander, so they can make a noticeable difference for many people. However, they work best when combined with other allergy control measures like regular cleaning, using dust-proof bedding, and keeping windows closed during high pollen days.

Some people notice improvement in allergy or asthma symptoms when they:

Limit high-histamine foods such as fermented foods, aged cheese, tomatoes, spinach, and seafood.
Increase foods rich in vitamin C, omega-3 fatty acids, magnesium, and antioxidants. They are found in fruits, nuts, green tea, and vegetables.
Stay hydrated and get adequate sleep to help the body regulate inflammation.

I hope this answers your query.

Please let me know if I can assist you further.

Thank you.