Q. Is it possible to have infertility due to low progesterone levels?

Answered by Dr. Sameer Kumar and medically reviewed by Dr. Divya Banu M


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Hello doctor,

I recently took a women's health test to test my hormones. I just got my results back and my Progesterone level is extremely low where as my Estradiol level is in the normal range. I have dealt with many irregular periods since I was young and have not been able to conceive a child with my husband and now I think I know why. I was wondering if my results can be looked at by a doctor to give me anymore information on what is going on with my test results. I am only 25.

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Dr. Sameer Kumar
Infertility, Obstetrics And Gynaecology


Welcome to icliniq.com.

The reports are fairly normal including the hormonal profile but the progesterone levels (attachment removed to protect patient identity). If these levels are from the proliferative phase then they can be considered normal, however, if from the luteal phase, then they are definitely low. Considering that LH was 11, this test may have been done around day 10 to 14 of your cycle, was it?

In cases of progesterone deficiency, one tends to get anovulatory cycles and also shortened cycles with mid cycle bleeds and irregular shedding with often passage of clots, so if not so and if you are experiencing delayed irregular cycles then cause is likely PCOS and not progesterone per se. Also, important in any fertility evaluation is the the male fertility factor. It is important to learn if the semen analysis report of your partner is normal or not, whether the quality and quantity of his sperms are good or not, so please share his semen analysis report as well for review.

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