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What are the advanced prostate cancer treatment options?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been diagnosed with advanced prostate cancer, confirmed by elevated PSA levels, a positive biopsy, and imaging that shows bone metastases. I am 61 years old. What are the most effective treatment options for metastatic prostate cancer? Are there therapies that can slow disease progression, manage symptoms, and improve quality of life? What is the primary focus of care in cases where the cancer has spread to the bones?

Kindly help.

Answered by Dr. Mona Kamal

Education:

Master in Pathology

Professional Bio:

Dr. Mona Kamal is a highly experienced pathologist and general practitioner with over 41 years of clinical expertise. She earned her Bachelor of Medicine, Bachelor of Surgery (M.B.Ch.B.) degree in 1982 and a Master’s degree in Pathology in 1989, both from Alexandria University, Egypt. Throughout her extensive career, Dr. Kamal has consulted with over 200 patients, demonstrating a strong commitment to accurate diagnostics and comprehensive patient care. She currently practices at Shifa Lab in Alexandria, where she applies her deep knowledge of pathology alongside general medicine to provide precise and compassionate healthcare services.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Advanced prostate cancer is aggressive, with a high likelihood of spreading beyond the prostate to other areas, including the bones. Treatment at this stage focuses on slowing progression, managing symptoms, and improving quality of life.

The probable cause is aggressive prostate cancer. The probable diagnosis is prostate cancer (a type of cancer that develops in the prostate gland, affecting the male reproductive system), with a Gleason score (a grading system used to assess the aggressiveness of prostate cancer based on the patterns of cancer cell growth in tissue samples) over 8, indicating high-grade cancer.

Treatment plan:

1. Radiotherapy: Delivered alongside androgen deprivation therapy (ADT) for 18 to 24 months to suppress androgen (the fuel for prostate cancer growth).

Purpose: Control cancer growth and limit further metastasis (spread).

2. Radical prostatectomy with pelvic lymphadenectomy: Surgical removal of the prostate and affected lymph nodes in select cases of advanced disease.

3. Chemotherapy: Systemic therapy targets cancer cells throughout the body and reduces disease burden.

4. Immunotherapy: Helps limit metastasis and boost the body’s immune response to cancer.

I hope this helps.

Revert with the answer to assist further.

Thank you, and take care.

Answered by Dr. Mona Kamal
Medically reviewed by iCliniq medical review team
Published At January 25, 2025
Reviewed At November 25, 2025

Education:

Master in Pathology

Professional Bio:

Dr. Mona Kamal is a highly experienced pathologist and general practitioner with over 41 years of clinical expertise. She earned her Bachelor of Medicine, Bachelor of Surgery (M.B.Ch.B.) degree in 1982 and a Master’s degree in Pathology in 1989, both from Alexandria University, Egypt. Throughout her extensive career, Dr. Kamal has consulted with over 200 patients, demonstrating a strong commitment to accurate diagnostics and comprehensive patient care. She currently practices at Shifa Lab in Alexandria, where she applies her deep knowledge of pathology alongside general medicine to provide precise and compassionate healthcare services.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

Master in Pathology

Professional Bio:

Dr. Mona Kamal is a highly experienced pathologist and general practitioner with over 41 years of clinical expertise. She earned her Bachelor of Medicine, Bachelor of Surgery (M.B.Ch.B.) degree in 1982 and a Master’s degree in Pathology in 1989, both from Alexandria University, Egypt. Throughout her extensive career, Dr. Kamal has consulted with over 200 patients, demonstrating a strong commitment to accurate diagnostics and comprehensive patient care. She currently practices at Shifa Lab in Alexandria, where she applies her deep knowledge of pathology alongside general medicine to provide precise and compassionate healthcare services.

This doctor is not available for online consultations on the platform anymore.

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