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Is it safe to get pregnant with an enlarged spleen?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have a hemoglobin C, and an enlarged spleen (7 inches), my doctor said as long as it does not hurt we will keep it. I do not sleep well because I feel like there is a big heavy ball in my stomach moving. I gave birth two years ago and I want to have another baby. My question is: is it safe to be pregnant with an 18 cm spleen? Is there a risk of splenectomy while I am pregnant? Is it safe to be pregnant without a spleen?

Please guide.

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

You are having hemoglobin C hemoglobinopathy leading to hemolysis and hence splenomegaly is present. Your hemoglobin level also should be checked.

In this case, as the cell turnover is high, folic acid is prescribed. If a splenectomy is done, in pregnancy, there are chances of infections and other complications according to a few studies.

An enlarged spleen creates trouble in pregnancy as uterine growth in pregnancy is affected, and enough space might not be available as the spleen is much enlarged. So, at this point, in my opinion, you should wait for some time.

And, before planning for conception, consult a gynecologist for examination and discuss these issues, and accordingly plan the pregnancy.

I hope this helps you.

Take care.

Medically reviewed by iCliniq medical review team
Published At January 10, 2018
Reviewed At June 26, 2026

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

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