Common "Hemoglobinopathy" queries answered by top doctors | iCliniq


Hemoglobinopathy is a class of diseases in which there is an anomalous generation or irregular structure formation of the haemoglobin molecule. It is an inherited disorder. This group of diseases comprises haemoglobin C disease, haemoglobin S-C disease, sickle cell anaemia, and thalassemia.

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Is pregnancy safe for women with enlarged spleen?

Query: Hello doctor, I have a hemoglobin C, and an enlarged spleen (7 inches), my doctor said as long as it does not hurt we will keep it. I do not sleep well because I feel like there is a big heavy ball in my stomach moving. I gave birth two years ago and I want to have another baby. My question is: is i...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to You are having hemoglobin C hemoglobinopathy leading to hemolysis and hence splenomegaly is present. Your hemoglobin level also should be checked. In this case, as the cell turnover is high, folic acid is prescribed. If a splenectomy is done, in pregnancy, there are...  Read Full »

Can HbE trait in mother affect the children?

Query: Hello doctor, The last few days my wife says that she feels sick. After that, I took my wife to the doctor. She suggested a few tests named HB electrophoresis, ferritin, TSH, PPBS, USG lower abdomen, CBC, PBF and urine test. Result:Hb%: 10.2, platelet-266000, RBC-4.28, WBC-7300, MCV-74, HCT/PCV-32...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to The serum ferritin level is not high in every case of hemolytic anemia. Your electrophoresis report is suggestive of HbE (attachment removed to protect patient identity). It is a case of a mild form of hemolytic anemia. In that case, the ferritin level might not be rais...  Read Full »

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