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Can unprotected sex cause sexually transmitted disease?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I recently had unprotected sex and have started experiencing some troubling symptoms. I have noticed sores on my genitals, a rash on my hands and feet, and swollen lymph nodes. I am concerned that I might have contracted a sexually transmitted infection, possibly syphilis or gonorrhea. I recently had some blood work done, and the results showed elevated white blood cells, along with a positive VDRL (Venereal disease research laboratory test) test. I am worried about what this could mean and would like to know what steps I should take next to get a confirmed diagnosis and start treatment. Could you also advise on the specific treatments for syphilis and gonorrhea that I should consider?

Thank you.

Answered by Dr. Raveendran S R

Education:

MBBS

Professional Bio:

Dr. Raveendran S R is a dedicated diabetes specialist and sexual medicine expert committed to providing evidence-based, confidential, and patient-centered care. With strong clinical and academic experience, he specializes in managing diabetes, erectile dysfunction, male infertility, performance concerns, and other men’s health conditions through structured and scientifically guided treatment approaches. Dr. Raveendran focuses on accurate diagnosis, personalized treatment plans, and long-term health improvement while ensuring patient comfort and privacy. Known for his compassionate and professional approach, he believes in clear communication and helping patients make informed decisions to improve their overall health, confidence, and quality of life.

This doctor is not available for online consultations on the platform anymore.

Hello,

I can understand your concern.

Your symptoms and results strongly suggest that you may have contracted syphilis, a sexually transmitted infection (STI). Elevated white blood cells indicate a disease that could be related to syphilis or another STI, like gonorrhea.

I suggest the following steps to confirm the diagnosis.

  • Plan for a confirmatory test, such as the TPHA (Treponema pallidum hemagglutination assay), to definitively diagnose syphilis.

  • Some other tests include:

  • HBsAg (Hepatitis B surface antigen)

  • Herpes simplex virus (HSV) 1+2 IgG, IgM,

  • Chlamydia Trachomatis IgG , IgM (immunoglobulins)

  • Urine complete

  • HPV PCR swab test

  • HIV(human immunodeficiency virus) 4th Gen Antigen/antibody test

If syphilis is confirmed, Penicillin G is the standard treatment. It is usually administered as an injection, and the number of doses depends on the stage of the infection:

  • For primary, secondary, or early latent syphilis, a single dose of Benzathine penicillin G is suggested.

  • For late latent syphilis: Three doses of Benzathine penicillin G at weekly intervals is suggested.

If you are also diagnosed with gonorrhea, the standard treatment is a combination of Ceftriaxone (an injection) and Azithromycin (an oral antibiotic). This dual therapy helps address possible co-infection with chlamydia, which often occurs alongside gonorrhea.

Also, consider the following things :

  • It is essential to inform any recent sexual partners so they can get tested and treated if necessary.

  • After treatment, follow-up tests are necessary to ensure the infection has been entirely eradicated.

Going forward, consider using protection during sexual activity and getting regular STI screenings to protect your health and that of your partners.

I hope this was helpful.

Thank you.

Medically reviewed by iCliniq medical review team
Published At September 23, 2024
Reviewed At August 7, 2025

Education:

MBBS

Professional Bio:

Dr. Raveendran S R is a dedicated diabetes specialist and sexual medicine expert committed to providing evidence-based, confidential, and patient-centered care. With strong clinical and academic experience, he specializes in managing diabetes, erectile dysfunction, male infertility, performance concerns, and other men’s health conditions through structured and scientifically guided treatment approaches. Dr. Raveendran focuses on accurate diagnosis, personalized treatment plans, and long-term health improvement while ensuring patient comfort and privacy. Known for his compassionate and professional approach, he believes in clear communication and helping patients make informed decisions to improve their overall health, confidence, and quality of life.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Raveendran S R is a dedicated diabetes specialist and sexual medicine expert committed to providing evidence-based, confidential, and patient-centered care. With strong clinical and academic experience, he specializes in managing diabetes, erectile dysfunction, male infertility, performance concerns, and other men’s health conditions through structured and scientifically guided treatment approaches. Dr. Raveendran focuses on accurate diagnosis, personalized treatment plans, and long-term health improvement while ensuring patient comfort and privacy. Known for his compassionate and professional approach, he believes in clear communication and helping patients make informed decisions to improve their overall health, confidence, and quality of life.

This doctor is not available for online consultations on the platform anymore.

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