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Is stem-cell therapy safe and effective?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been looking into stem-cell therapy for chronic conditions, but I am worried about its safety and effectiveness. There are so many clinics offering treatments for arthritis, neurological diseases, and even anti-aging, but it is hard to tell which ones are legitimate.

How does stem-cell therapy actually work, and which conditions have responded best to it? Is there solid scientific evidence supporting its use for osteoarthritis, multiple sclerosis, or spinal cord injuries? Safety-wise, I am concerned about immune rejection, abnormal cell growth, and the risk of cancer. Since many clinics offer treatments that are not FDA-approved, how can I make sure a therapist follows proper medical protocols?

Also, are autologous stem cells safer than donor-derived ones? Any insights into promising clinical trials or new developments in regenerative medicine would be helpful. I am trying to figure out if stem-cell therapy is worth considering and how to find a trustworthy provider.

Please help.

Thank you.

Answered by Dr. Sally Attalah

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I read your query and can understand your concern.

Stem cell therapy (a medical treatment that uses stem cells to repair, replace, or regenerate damaged tissues and organs) is a relatively new procedure, and more research is needed to determine its long-term success. However, early studies suggest it can effectively treat knee pain and injuries, with success rates of 70 to 80 percent for mild to moderate knee osteoarthritis (a degenerative joint disease that causes cartilage breakdown, leading to pain, stiffness, and reduced mobility).

Also known as regenerative medicine, stem cell therapy promotes the repair of diseased, dysfunctional, or injured tissue using stem cells or their derivatives. It represents the next step in organ transplantation, using cells instead of donor organs, which are in limited supply.

Side effects of stem cell therapy:

  1. Low blood cell counts.

  2. Infection.

  3. Bleeding.

  4. Anemia.

  5. Graft-versus-host disease (GVHD).

  6. Veno-occlusive disease (VOD).

  7. Digestive issues.

  8. Skin and hair problems.

Sources of stem cells:

Autologous stem cell therapy: Uses the patient’s own stem cells, commonly sourced from bone marrow, making it the most effective and accessible option.

Cord blood and cord tissue stem cells: These are the purest and youngest tissue-specific stem cells, collected at birth and known for their rapid and efficient function compared to adult stem cells.

Choosing a trustworthy stem cell clinic:

  1. The clinic should be owned and operated by an experienced stem cell physician.
  2. Injections should be performed by a trained specialist.
  3. X-ray-guided injections should be used for spine and joint treatments.

I hope this helps.

Kindly revert so I can assist you further.

Thank you.

Medically reviewed by iCliniq medical review team
Published At May 4, 2025
Reviewed At July 2, 2026

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

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