Common "Synacthen Test" queries answered by top doctors | iCliniq

Synacthen Test

Synacthen test is a screening procedure used to test adrenal insufficiency. This procedure works by measuring serum cortisol levels before and after an injection of synthetic Adrenocorticotropic hormone. If the adrenal is functioning correctly, the cortisol level should be >420nmol/L at 30 minutes after the Synacthen.

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What is the treatment for prolonged sodium loss in my dad?

Query: Hello doctor, My father underwent a brain aneurysm repair one and a half years ago, after which, he is having a constant loss of sodium. He is taking one Tolsama 15 mg tablet every alternate day to stabilize his sodium levels. He is also currently taking Encorate Chrono 500, Absolut 3G, Nexfolin and...  Read Full »


Dr. Shaikh Sadaf

Answer: Hello, Welcome to icliniq.com. I read your query about your father and it appears that he has SIADH (syndrome of inappropriate antidiuretic hormone secretion). It commonly occurs after a brain surgery, due to excessive fluids and use of diuretics. The sodium levels usually return to normal soon, ...  Read Full »

Does Synacthen test provide accurate results regarding pituitary gland function?

Query: Hi doctor, I was diagnosed with Cushing's disease, which caused a high level of cortisol before two years. The tumor size was 2 mm. I had surgery and the pituitary gland tumor was removed. Then, I am having a low level of cortisol and T4. After the operation, I am taking Hydrocortisone (10 mg or 5 m...  Read Full »


Dr. Hardik Nareshbhai Rajyaguru

Answer: Hi, Welcome to icliniq.com. I understand your question. I have noted all your laboratory test results (attachment removed to protect patient identity). The only doubt I want to clear is about the medicine. Did you mention cortisol PM (Post meridiem) part as after medicine? Which was the medicine you...  Read Full »

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