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What are the patient assistance programs available for asthma?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

Our situation is very bad due to my son's asthma. Now, he is 17 years old, and he has been hospitalized five times this year despite undergoing intensive treatments. The use of multiple high-dose steroids has led to considerable weight gain, mood fluctuations, and the risk of long-term health issues. His pulmonologist has recently recommended Tezspire, but our insurance has outright denied coverage, labeling it as "experimental." The cost of this medication is prohibitively high for us. He has had to withdraw from his final year of high school twice because of respiratory issues, and he is witnessing his academic and athletic aspirations fade away. His current treatment regimen includes several inhalers, oral steroids, and two unsuccessful biologic therapies. Are there any patient assistance programs available? What impact could Tezspire have on his condition? We are observing a steady decline in his quality of life.

Kindly help.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Dealing with severe asthma that does not respond to treatment can be incredibly challenging. Considering his frequent hospital visits, the side effects from steroids, and his diminishing quality of life, Tezspire (Tezepelumab) could potentially be a significant breakthrough if he can obtain it.

What impact could Tezspire have?

Tezspire distinguishes itself from other biologics by targeting TSLP, a crucial factor in the inflammatory process, rather than focusing on eosinophils or IgE. This unique mechanism allows it to be effective regardless of eosinophil levels or allergic conditions, which is particularly important since your son has not responded to two previous biologic treatments.

Possible advantages supported by clinical evidence:

  1. A 50–70 percent decrease in exacerbations, which could significantly reduce hospital admissions.

  2. Reduced reliance on steroids, contributing to better weight management and mood stability.

  3. Enhanced lung function and symptom management.

  4. Improved overall quality of life, allowing for more participation in school and sports with fewer restrictions.

Given his severe and uncontrolled asthma despite various treatments, he qualifies for consideration of Tezspire as a medically necessary option, and there are avenues to pursue insurance coverage.

Patient support and insurance appeals:

1. Tezspire support program.

2. Insurance denial appeals.

His pulmonologist should initiate an appeal, emphasizing the medical necessity of Tezspire due to:

  1. Frequent hospitalizations.
  2. Inadequate response to multiple standard treatments and biologics.
  3. Adverse effects and toxicity from steroids.
  4. A peer-to-peer review with the insurance provider may also be required.

State assistance and nonprofit resources:

Certain states offer high-risk insurance pools or asthma-related foundations that can assist with covering expenses.

I hope this information helps you.

Feel free to ask further queries.

Thank you.

Medically reviewed byiCliniq medical review team

Published At May 25, 2025
Reviewed AtJune 4, 2025

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