What is the use of Tezspire in severe asthma?

Question

Hello doctor,

My 19-year-old son suffers from severe asthma, which has significantly worsened this year despite his use of inhalers, nebulizers, and oral steroids. He has been hospitalized three times in the last four months, with his most recent stay in the ICU due to dangerously low oxygen levels. His pulmonologist has suggested starting Tesspire injections, although he noted that the treatment is quite costly. We are feeling desperate, as he is missing college classes and rarely leaves his room due to the fear of asthma triggers. I would like to know how effective this treatment is in comparison to his current regimen. What are the associated risks? Will he require these injections indefinitely? Our insurance has a high deductible, and we are concerned about the financial implications, but his current quality of life is extremely poor.

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Tesspire (Benralizumab) is a medication designed for the management of severe asthma, specifically targeting eosinophilic asthma. Our initial step will be to identify the specific subtype of asthma your son has. If it is determined to be eosinophilic asthma, Benralizumab may be an appropriate treatment option, as it works by reducing eosinophils in the airways, which are responsible for inflammation.

Benralizumab is administered via injection every four weeks, with the treatment duration being determined by your healthcare provider based on the level of control achieved.

The most common side effects are related to the injection site, which may include redness, swelling, and pain.

Recommended investigations include: Eosinophil count.

Potential diagnosis: Severe asthma.

Proposed treatment plan: Benralizumab every four weeks.

I hope this information helps you.

Feel free to ask further queries.

Thank you.