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How to know if Tezepelumab is working in adolescent girls?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My daughter is 19 years old and has had severe asthma for six years, and just received her first Tezspire (Tezepelumab) injection yesterday. She has developed a weird rash on her arms and is complaining of joint pain. Are these expected side effects? How many doses will it take before we know if it is actually helping her breathe? Her previous biologic did not work at all, even after eight months of trying.

Kindly help.

Answered by Dr. Sally Attalah

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have read your query and can understand your concern.

Tezspire (Tezepelumab) has certain side effects:

  1. Back and joint pain.
  2. Sore throat.
  3. Allergic reaction.
  4. Injection site reaction.
  5. Rash.
  6. Red, itchy, swollen, or inflamed eyes.

I suggest you take Tezspire (Tezepelumab) as prescribed. Tezspire (Tezepelumab) is administered once every four weeks.

Tezspire (Tezepelumab) starts to work after the first dose, but it may take several weeks before noticeable improvement in asthma symptoms. In clinical studies, some individuals experienced symptom relief as early as two weeks after the initial dose.

The probable cause could be asthma.

I hope this helps.

Thank you.

Medically reviewed by iCliniq medical review team
Published At July 19, 2025
Reviewed At July 22, 2025

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

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