Q. What is the treatment for thalassemia major?

Answered by
Dr. Sumit Srivastava
and medically reviewed by Dr. Sneha Kannan
This is a premium question & answer published on Feb 15, 2016 and last reviewed on: Apr 18, 2019

Hi doctor,

I am a thalassemia major patient. My spleen size is 21. How to reduce my spleen size? And also I want to increase my weight? My age is 21. How much percentage risk is present in the unrelated donor stem cell transplant? My ferritin is 1500 and weight is 48 kg. Please suggest some solution.



Welcome to

At present there is no way to reduce the spleen size.

Diet for thalassemia major patient should include plenty of fruits and vegetables and protein rich diet. Taking vitamin C supplements will help to increase the immunity of the body.

Bone marrow transplantation is a curative treatment for thalassemia major (symptoms of severe anemia from childhood). Bone marrow transplantation can be done if you do not have any long-term complication of thalassemia major.

Adult thalassemia patients are higher risk patients for transplant-related toxicity due to an advanced phase of disease and have a cure rate of 60 to 70% with current treatment protocol. There is 90% long-term survival rate in patients with favorable characteristics such as young age, HLA (human leukocyte antigen) match and no organ dysfunction.

I would suggest you to consult a hematologist who can guide you better.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Is it advisable to do bone marrow transplant for acute leukemia?

Hello doctor,My friend's brother is diagnosed with blood cancer and has gone through first chemotherapy three weeks ago ...   Read full

What is the percentage of living in refractory T-all pulmonary Koch's disease?

.. your query and attached reports (attachment removed to protect patient identity), my opinion is as follows: Pulmonary tuberculosis is under control and continuation of therapy is necessary. However, the main problem is leukemia, which is not respo...   Read full

Preimplantation Genetic diagnosis

.. couples have their embryos tested for any genetic abnormality before implantation. It is one of the newly developed techniques to avoid IVF failure .. ...   Read full


Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Balantidiasis - Causes, Signs and Symptoms, Diagnosis, Treatment, and Prevention
Balantidiasis is a rare bacterial infection caused by a parasite called Balantidium coli. Read the article below to know...  Read more»
JAK Inhibitors in Treating Rheumatoid Arthritis
Doctors mainly suggest JAK or Janus kinase inhibitors for patients with rheumatoid arthritis to ease their symptoms. Rea...  Read more»
Importance of Sex Hormones - Types, Functions, Normal Ranges, and Roles
Sex hormones are steroids produced in the body that control sexual development, pregnancy, and overall health. Read belo...  Read more»

Ask your health query to a doctor online?

Ask an Internal Medicine Physician Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.