Common "Thrombocytopenia" queries answered by top doctors | iCliniq


Thrombocytopenia is a condition having a low platelet count in the blood. It can occur due to a bone marrow disorder or problems in the immune system. It can also occur due to a side effect of certain medications. There is the appearance of small red dots on the skin, bleeding gums, nose bleeding, bruising, blood with vomiting, and headaches. It is managed by transfusion of blood or platelets, plasma exchange, medications, and surgery.

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What steps can be taken to address my mother's low platelet count and adverse reactions to anti-tuberculosis treatment?

Query: Hello doctor, My 57-year-old mother was diagnosed with tuberculosis (TB) two months ago based on exclusion, as her initial tests returned negative. However, she exhibited symptoms such as enlarged lymph nodes in the chest, low fever, and night sweats. A biopsy ruled out lymphoma and sarcoma. She wa...  Read Full »

Dr. Srivastava, Sumit

Answer: Hello, Welcome to I read your query and can understand your concern. Based on the analysis of your reports (attachment removed to protect the patient's identity), the bone marrow report indicates that there are normal megakaryocytes present, which suggests that the bone marrow is pro...  Read Full »

I am a 33-year-old male having a low platelet range and giant platelets since the last month. Why?

Query: Hello doctor, I am a 33-year-old male with having low platelets range of 60000 to 85000 platelets per microliter of blood since the last month. The first time checked for platelet was one month ago. Giant platelets are seen in PBS (150000 around peripheral smear). No atypical cells were seen. TSH, T...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I understand your concern. According to the history provided, your MPV (mean platelet volume) value is high, platelet low, and giant platelet present in the smear. Hence thrombocytopenia (low platelet) can be from increased platelet destruction (giant platelet counted as...  Read Full »

My three-year-old son has been suffering from a low platelet count despite taking medications. Please help.

Query: Hello doctor,My three-year-old son has been suffering from a low platelet count (1,20,000 platelets per microliter of blood) for about six months. Approximately one year ago, he was diagnosed with a low hemoglobin count due to iron deficiency and was treated with iron supplement syrup for eight mont...  Read Full »

Dr. Mubashir Razzaq Khan

Answer: Hello, Welcome to understand your concern. For a platelet level of 1,20,000 platelets per microliter of blood, no treatment is needed. Unfortunately, I could not open your reports file. The management of low platelets or thrombocytopenia includes:Grade 1 thrombocytopenia: Platelet coun...  Read Full »

Did COVID-19 infection reduce my blood platelet count?

Query: Hi doctor, I have been an immune thrombocytopenia patient for the last seven years. Last month, I was diagnosed COVID positive, and recently I had a CBC, and my platelet count was reflecting as 82000/μl, earlier it was 163000/μl for over six months. No bleeding or blood clots in the body were noti...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I understand your concern. Your platelets count is low, and the reason is immune thrombocytopenia (ITP), in which antibodies act against the patient's platelet. Your platelet count is less due to ITP and not due to past COVID infection. I suggest you continue the immun...  Read Full »

What is the normal platelet count and what is thrombocytopenia?

Query: Hi doctor, My platelet count is low for the past month, between 115000 to 130000 platelets per mcL, which I found during my regular body check-up. I do have any previous issues related to this. Please guide me.  Read Full »

Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to Your counts are clinically insignificant. Low platelet count is also called thrombocytopenia. In grade 1 thrombocytopenia, platelet count ranges between 75000 to 150000 platelets per mcL. No action is needed. Just follow-up is enough. In grade 2 thrombocytopenia, plat...  Read Full »

Is it necessary for recovered COVID-19 patients to get the COVID vaccines?

Query: Hi doctor, I was diagnosed with aplastic anemia a few years back, and I underwent ATG treatment. I was on Cyclosporine for three years with slow tapering. Partial remission. At present Hb -11, WBC- 5300 , platelets- 48000. I could not consult a regular doctor because of COVID-19. Can I take the COVI...  Read Full »

Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to If you had COVID-19 infection previously for once, you can get vaccinated after three months of convalescence with only one dose of vaccine. No second dose is needed. If you had COVID-19 infection twice previously, no vaccine is needed. If you did not have COVID-19 in...  Read Full »

Why is the platelet count decreasing even after platelet transfusion?

Query: Hello doctor, My mom's platelet count was 6,000 and they did platelet transfusion for six pints and it came about 100,000 and after that, today again it became 13,000. What will be the disease condition and what is the treatment to be followed?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to You have not mentioned at what time she got her platelet transfusion and now after how many days the platelet count has been decreased. Dengue, immune thrombocytopenia purpura, uremia, malaria, blood septicemia, drugs, platelet functional disorder, consumptive coagul...  Read Full »

I have had genetic testing done for essential thrombocytopenia. Can you please interpret the results?

Query: Hello doctor, My preliminary diagnosis was essential thrombocythemia. They did genetic testing it showed JAK2 mutation (v617f) at about a 25 % allele burden. However, it also came back showing an IDH2 mutation. This tends to be found more in brain tumors and acute myeloid leukemia. The mutations fo...  Read Full »

Dr. Mubashir Razzaq Khan

Answer: Hello, Welcome to Thank you for your query. Elevated platelets are seen in iron deficiency anemia, post-splenectomy, acute blood loss, multicentric castleman disease, CML, 5q syndrome, primary myelofibrosis, rheumatologic, inflammation, drug-induced, and very rarely, it could be a part ...  Read Full »

How to manage microcytic hypochromic anemia with thrombocytopenia?

Query: Hi doctor,My partner was admitted to the hospital for a low platelet count, and she was asymptomatic. They did a blood transfusion and gave corticosteroids. There was no improvement in her platelet level. The doctor suggested me to consult a hematologist. On her recent reports, her platelet count wa...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I have gone through the attachment (attachment removed to protect patient identity). Her platelet count is low in the manual as well as on the cell counter. So infective etiology has to be ruled out first. If there is no sign of any infection, then ultrasonography abdom...  Read Full »

I have a runny stomach and black stools after the flu. Why?

Query: Hello doctor, I had the flu for two days. That included a fever, sore throat, and runny nose with a dry cough. The flu went away and now I just have a cough, but I have developed a rash behind my ears and a runny stomach in which my stool is black.  Read Full »

Dr. Settipalli Saravan Pramod

Answer: Hello, Welcome to It seems like a hemorrhagic fever such as dengue in which the patient presents with a bleeding manifestation of melena (black-colored stools), bleeding gums, any hemorrhagic rashes, or hematuria, etc.Black-colored stools indicate that blood is leaking from somewhere in...  Read Full »

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