HomeAnswersEndocrinologytsh levelMy TSH level increased from 0.19 to 86 uIU/mL despite taking medication. Why?

What could cause elevated TSH levels despite taking medications?


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At November 7, 2023
Reviewed AtNovember 7, 2023

Patient's Query

Hello doctor,

My TSH level increased from 0.19 to 86 uIU/mL in 60 days; it was 157 uIU/mL in the next six days. That, too, is when I am taking 75 mcg as suggested by the doctor. Please help me

Thank you.


Welcome to icliniq.com.

Your full replacement dose will be 150 to 175 mcg daily. (you may not need the full replacement dose yet, but maybe your requirement has gone up from the initial 50 mcg).

But saying so, I think it is strange the TSH (thyroid stimulating hormone) went from 0.19 to 86 uIU/mL.

Please note that TSH going from 86 to 157 means almost the same, and no need to panic.

Maybe other medicines you took after the ACL surgery may have interfered with the absorption of thyroxine.

I recommend increasing the dose to 125 mcg and taking it on an empty stomach and with no food or drinks, or any other medicines for at least 1 hour.

And repeat the TSH along with Free T4 after 60 days.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Thiyagarajan. T
Dr. Thiyagarajan. T


Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Ask your health query to a doctor online


*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy