Introduction:
As we can all appreciate, progesterone is a naturally occurring hormone. It is a steroid hormone, and it is essential for the regulation of menstruation and ovulation. Progesterone is produced significantly by the ovaries and other parts involved in the reproduction process.
It can also be secreted in a smaller amount by utilizing the adrenal glands in both females and males. The levels of this hormone in the body are necessary for menstruation and pregnancy. People with low levels of the progesterone hormone face difficulties with their menstrual cycles and the ability to conceive. A paramount decrease in progesterone levels can result in uterine bleeding, infertility, and certain serious complications.
What Is Progesterone Micronized Insert?
Progesterone micronized insert, or progesterone vaginal insert, is a medication to be inserted into the vagina two to three times a day. It treats low concentrations of progesterone in the body.
So, this medication markedly increases the progesterone levels in women taking fertility treatments since such treatments generally tend to reduce the progesterone levels. It is used primarily for menstruation and getting pregnant.
Women should use this medication as directed by their physician. One should not take progesterone micronized by oral means. This medication is for use and application only in the vagina.
What Is the Use of a Progesterone Micronized Insert?
Progesterone vaginal medication helps treat low progesterone levels in women. This medication constitutes progesterone, which typically replaces low progesterone levels in the body. This medication is used in conditions that lack an appropriate progesterone concentration.
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Progesterone micronized inserts are used to treat fertility problems or infertility in women who do not have an adequate amount of naturally occurring steroid hormones called progesterone.
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Since progesterone hormone is crucial in maintaining the initial stages of pregnancy, this medication can be used to maintain pregnancy in some instances.
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This vaginal insert medication is also prescribed for restoring menstrual cycles in females with menstruation problems or whose menstrual cycles have been halted.
How Does the Progesterone Micronized Insert Work?
Progesterone is a naturally occurring endogenous steroid hormone typically secreted by the adrenal gland, placenta, and ovary. Hormones have a great role in the system, as they are the chemical messengers that tell the body how to function.
Progesterone plays a significant role in the reproductive system by supporting and enhancing menstruation and maintaining the early stages of pregnancy. The levels of progesterone in the body are crucial for its significance.
A low concentration of progesterone can lead to complications during pregnancy. The predominant function of progesterone in the body is to guard the lining of the uterus (endometrium) for the implantation and growth of fertilized eggs. In the absence of pregnancy, the endometrium begins shedding during the menstrual time. If there is a conception (the process of conceiving), the progesterone hormone is increased to support the pregnancy.
Progesterone micronized insert is a vaginal treatment of progesterone in the case of inadequate progesterone levels. Here, progesterone helps in the transformation process of proliferation of endometrium into secretary one. It also increases endometrial (uterus lining) accessibility for embryo implantation. Progesterone now serves to maintain the pregnancy once the embryo is implanted.
How Should One Use a Progesterone Micronized Insert?
The doctors advise the appropriate dosage considering certain determinants like age, condition, and progesterone level. One should use the medication per the healthcare provider’s directions and the manufacturer’s label information on the leaflet. This medication is meant only for vaginal use. This medication comes in suppositories, so unwrap them and use them. Follow the instructions and insert this medication into the vagina only with the applicator. The doctors generally recommend applying it two to three times a day. If one becomes pregnant, it is generally recommended to continue the medication for ten weeks or as prescribed by the doctor.
What One Should Tell the Physician Before Taking This Medicine?
Physicians must know whether an individual has any of the following illnesses
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Vaginal cancer.
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Cervical cancer.
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Breast cancer.
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Heart conditions.
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Renal illness.
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Illness of the liver.
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Abortion.
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Bleeding in the vagina.
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Pregnant or breastfeeding women.
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Any unusual reactions to progesterone or any other drugs.
What Other Medications Could Interact With This One?
Avoid causing any other vaginal medications without the physician's advice. One must keep the physician informed about any other medications that are taken, over-the-counter medications, herbal remedies, and nutritional supplements. Moreover, a history of smoking and alcohol use should be disclosed to the physician. Some drugs that interact with this medicine are Carbamazepine and Rifampin.
What Are the Potential Side Effects of Progesterone Micronized Inserts?
Though the progesterone micronized insert is safe and effective, it could cause specific undesirable reactions in several cases. The most common side effects include the following, which do not require medical attention. However one should report them to healthcare providers if they are continuing and distressing.
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Bloating.
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Drowsiness.
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Irregular menstrual cycles.
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Mood swings.
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Nausea.
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Breast pain or discomfort.
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Application site vaginal irritation.
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Swelling of the hands, feet, and ankles.
Progesterone micronized inserts can induce serious adverse effects in rare cases. One should consider such severe side effects and seek professional help as soon as possible.
The serious side effects include the following.
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Signs of allergic reactions include hives, rashes, difficulty breathing, and swelling of the face and throat.
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Breast tissue changes, pain, and lumps
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Spinning sensation.
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Severe degrees of dizziness or drowsiness.
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Shortness of breath.
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Confusion.
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Painful or burning sensation while urinating.
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Unusual vaginal bleeding.
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Sudden vision problems, pain behind the eyes, and headaches.
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Symptoms of depression include mood changes, weakness, and sleep impairments.
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Signs of heart ailment include chest pain, discomfort, nausea, and sweating.
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Signs of liver problems include stomach pain, nausea, tiredness, loss of appetite, clay-colored stools, dark-colored urine, and jaundice.
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Signs of a stroke include sudden numbness, particularly on either side of the body, slurred speech, balance problems, and coordination problems.
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Signs of blood clots include chest pain, a warm feeling or redness in the legs, and coughing up blood.
Conclusion:
Progesterone micronized vaginal insert is a medication to be administered into the vagina. This medication contains a natural female hormone known as progesterone. Progesterone and other reproductive hormones help one conceive and maintain a pregnancy. This hormone also has a crucial role in menstrual cycles. So, a progesterone micronized insert containing progesterone hormone helps increase progesterone concentration in women with less. One must discuss the potential risks and benefits of a progesterone vaginal insert with the specialist and confirm whether it suits them.
