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Why does my allergy not go away with medications?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I appeared to have an allergic reaction to something nearly two weeks ago. I was given antihistamines and a seven-day course of steroids (Prednisolone 40 mg). The allergy seems to subside, but it keeps coming back.

I cannot be sure about the cause of this allergy. The skin around my eyes has been itchy and red since this morning. I have attached a photo of the initial flare-up.

Please help.
Answered by Dr. Thakare Sampada Avinash

Education:

MD

Professional Bio:

Dr. Thakare Sampada Avinash is a Cosmetologist and Dermatologist with expertise in managing skin, hair, and nail disorders as well as providing advanced cosmetic treatments. She is passionate about enhancing both skin health and aesthetic outcomes through evidence-based practices. She is skilled in the diagnosis and treatment of skin, hair, and nail conditions. She is well-versed in doing cosmetic dermatology procedures such as chemical peels, laser therapies, botox, fillers, and microdermabrasion.

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Hi,

Welcome to icliniq.com.

I understand your concern, and I have seen the attached photo (attachment removed to protect patient identity).

This is called acute urticaria with angioedema. It is basically an allergic reaction, which can be due to a change in diet, new medications, or idiopathic (sometimes the cause cannot be known). Since there is swelling on the lips and eyes, you should visit an emergency room.

You will need another course of oral steroids or injectable doses. Continue with the oral antihistamines. The oral steroids should be tapered from 40 mg to lower doses and then stopped. If stopped suddenly at 40 mg, there is a chance of recurrence. Consult your specialist doctor, discuss with them, and take the medicines with their consent.

Self-medication is not advised in this condition. Look out for symptoms like difficulty in swallowing or breathing. If they develop, visit a doctor as soon as possible.

Do not wait. I suggest you get the following tests done:

  1. CBC (complete blood count).
  2. ESR (erythrocyte sedimentation rate).
  3. Serum IgE (immunoglobulin E) levels.
  4. Urine routine microscopy.

I hope this has helped you.

Please feel free to reach out to me again if you have further queries.

Thank you.

Medically reviewed by Dr. K. Shobana
Published At June 19, 2017
Reviewed At June 22, 2026

Education:

MD

Professional Bio:

Dr. Thakare Sampada Avinash is a Cosmetologist and Dermatologist with expertise in managing skin, hair, and nail disorders as well as providing advanced cosmetic treatments. She is passionate about enhancing both skin health and aesthetic outcomes through evidence-based practices. She is skilled in the diagnosis and treatment of skin, hair, and nail conditions. She is well-versed in doing cosmetic dermatology procedures such as chemical peels, laser therapies, botox, fillers, and microdermabrasion.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Thakare Sampada Avinash
Dr. Thakare Sampada Avinash

Dermatology

Education:

MD

Professional Bio:

Dr. Thakare Sampada Avinash is a Cosmetologist and Dermatologist with expertise in managing skin, hair, and nail disorders as well as providing advanced cosmetic treatments. She is passionate about enhancing both skin health and aesthetic outcomes through evidence-based practices. She is skilled in the diagnosis and treatment of skin, hair, and nail conditions. She is well-versed in doing cosmetic dermatology procedures such as chemical peels, laser therapies, botox, fillers, and microdermabrasion.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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