Why does my allergy not go away with medications?

Question

Hi doctor,

I appeared to have an allergic reaction to something nearly two weeks ago. I was given antihistamines and a seven-day course of steroids (Prednisolone 40 mg). The allergy seems to subside, but it keeps coming back.

I cannot be sure about the cause of this allergy. The skin around my eyes has been itchy and red since this morning. I have attached a photo of the initial flare-up.

Please help.

Answer 1

Hi,

Welcome to icliniq.com.

I understand your concern, and I have seen the attached photo (attachment removed to protect patient identity).

This is called acute urticaria with angioedema. It is basically an allergic reaction, which can be due to a change in diet, new medications, or idiopathic (sometimes the cause cannot be known). Since there is swelling on the lips and eyes, you should visit an emergency room.

You will need another course of oral steroids or injectable doses. Continue with the oral antihistamines. The oral steroids should be tapered from 40 mg to lower doses and then stopped. If stopped suddenly at 40 mg, there is a chance of recurrence. Consult your specialist doctor, discuss with them, and take the medicines with their consent.

Self-medication is not advised in this condition. Look out for symptoms like difficulty in swallowing or breathing. If they develop, visit a doctor as soon as possible.

Do not wait. I suggest you get the following tests done:

CBC (complete blood count).
ESR (erythrocyte sedimentation rate).
Serum IgE (immunoglobulin E) levels.
Urine routine microscopy.

I hope this has helped you.

Please feel free to reach out to me again if you have further queries.

Thank you.