Q. I am taking Concerta XL for ADHD, but it is not working inspite of increasing the dosage. Why?

Answered by
Dr. Suresh Kumar G D
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 19, 2019 and last reviewed on: Nov 21, 2019

Hello doctor,

I have been taking Concerta XL for ADHD for 10 days now. I have started taking 18 mg per day and after seven days I increased it to 36 mg. However, I do not feel the effects anymore, initially, when I was taking 18 mg it was working, but it no longer works. Can you develop a tolerance to Concerta XL? Please help.

Dr. Suresh Kumar G D

Child Health Paediatrics Psychiatry


Welcome to icliniq.com.

Concerta XL needs to be gradually titrated up according to your age, body weight and clinical response, i.e improvement in symptoms and any side effects. I note that it is still early days since you commenced on Concerta. XL. You will not be developing tolerance in this timeframe. For your weight (92 kg), perhaps you may need a higher dose provided there are no contraindications. Discuss with your psychiatrist or treating team about titrating up to 45 mg a day or 54 mg a day. You will need to be regularly followed up, during the initial period of starting stimulants.

Also, try to follow cognitive behavioral techniques alongside medication for optimal management of ADHD (attention deficit hyperactive disorder) symptoms.

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