Autoimmune Disorder

The diseases caused when your body's immune system attacks your body, mistaking it for a foreign body, are called autoimmune diseases. Type 1 diabetes, rheumatoid arthritis, psoriasis, multiple sclerosis, systemic lupus erythematosus, and myasthenia gravis are a few examples of autoimmune diseases. The antinuclear antibody test (ANA) is used to diagnose them.

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I have subclinical hyperthyroidism. Kindly suggest a treatment.

Query: Hello doctor, I have subclinical hyperthyroidism with some sort of active nuts and thyroid stimulating hormone at 0.09 and an autoimmune process. Kindly help.  Read Full »

Dr. Thiyagarajan. T

Answer: Hello, Welcome to What symptoms do you have? Did you also check free T4 and T3 besides TSH (thyroid stimulating hormone)? If not done, please do a thyroid uptake scan. If you are symptomatic, you can be treated even if the hyperthyroidism is subclinical. Please send more informati...  Read Full »

Does vasoconstriction occur due to an allergy to antihistamines?

Query: Hi doctor, I am having major vasoconstriction problems. I would like to know if my daily antihistamines intake is causing this problem. I am taking Loratadine and Fexofenadine hydrochloride daily for allergies.  Read Full »

Dr. Naval Mendiratta

Answer: Hi, Welcome to I would like to know in detail, what you mean by vasoconstriction problems? Is it affecting your hands or your feet or anywhere in the nasal bed? Do you experience any bluish discoloration of the nails or hands? Do you have any pain in the hands or feet? Do you have ul...  Read Full »

My 28-year-old wife has been diagnosed with Wegener's granulomatosis. Is this disease curable?

Query: Hello doctor, I married a girl who is 28 years old now. We got married a year ago. She was diagnosed with Wegener's granulomatosis. She is taking medications and injections. I learned about the severity of the disease, so I started feeling low. I am attaching her blood work and reports. I need to kn...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I have seen these reports (attachments removed to protect the patient's identity) in the past also. From these reports, I can say that she is in remission, which means the disease is under control. I understand your concern as the disease is lifelong, and once it is ...  Read Full »

Had a sudden onset of AIHA. Please explain the relapse with AIHA.

Query: Hi doctor, I am 20 years old. I had a sudden onset of AIHA. At first, I had no response to steroid therapy, and after a week, I came back to normal. I want to know about the relapse with AIHA.  Read Full »

Dr. Girish Chandrakant Kamat

Answer: Hi, Welcome to Approximately 80 % of patients respond to corticosteroids at a dose equivalent to Prednisolone 60 to 100 mg per day and nearly two-thirds achieve complete remission (CR). The initial response takes several weeks. But an absence of a response for 21 days is considered as a...  Read Full »

What causes low-grade fever with swelling of glands in the neck for three months?

Query: Hi doctor, I have a low-grade fever for three months. I have three or four lumps on the left breast. There is a swollen gland in my neck and under my jaw. It swells and gets smaller. I have pain in my left shoulder and it crunches when I move it. I also have pain in my left elbow without injuries. ...  Read Full »

Dr. Sadaf Mustafa

Answer: Hi, Welcome to If you have night sweats, weight loss, and fever, then you need to worry about leukemia, lymphoma, mycobacterial infection, HIV (human immunodeficiency virus), and autoimmune disease. You need to do a peripheral smear, ANA (antinuclear antibody) with differentiation, ly...  Read Full »

My hands hurt for no reason, and I doubt if an autoimmune disease is a reason. Can you please help?

Query: Hi doctor, I think I have an autoimmune disease. Hands hurt for no reason at all. I tested negative for sjogren's syndrome, lupus, and rheumatoid arthritis. I am tired all the time and have no appetite. I am currently taking tablet Lexapro (Escitalopram Oxalate), tablet Adderall (Dextroamphetamine S...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hi, Welcome to Speckled antinuclear antibodies are seen in mixed connective tissue disease (MCTD) and scleroderma. If you have raynaud's phenomenon, do an echocardiogram (ECHO) to look for pulmonary artery hypertension, a high-resolution computed tomography (HRCT) of the chest to asse...  Read Full »

Does my symptoms point towards autoimmune disease?

Query: Hello doctor,Based on the following, do I have an autoimmune disease:An overall feeling of sickness.Irregular heartbeat sometimes.Swollen and painful joints.Swollen legs, ankles, fingers, and toes.Headaches sometimes.Shortness of breath.Psoriasis arthritis.Visual problems, burning, itching, very dry...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post. Things which favor the diagnosis of autoimmune disease in your case are as follows: Pain and swelling of joints. Puffiness of hands and feet. Dryness of mouth and eyes. Psoriasis. You need to be investigated for UCTD (undifferentiated...  Read Full »

What does a positive ANA test in a diabetic patient indicate?

Query: Hello doctor, My mother is 65 years old. She is a diabetic. For the past one month, she had fever, body pain, and joint pain. After a while, her leg started swelling, and slowly the blood platelet count came to 28000. She got admitted to the hospital and was on Xone antibiotics and Dolo 650 with tr...  Read Full »

Dr. Salah Saad Hassan Shoman

Answer: Hello, Welcome to I have gone through your question and understood your concerns. Autoimmune attacks that lead to decreased platelet count (thrombocytopenia) are mostly associated with systemic lupus syndrome or can be associated with rheumatoid arthritis in case there is an associated...  Read Full »

What causes the development of febrile seizures in a 3-year-old?

Query: Hello doctor, There are recurrent unexplained fevers in a 3-year-old female that have caused a febrile seizure. All blood work came back well, and she has no cold or flu. They even checked for a UTI and found nothing. She very easy to gets sick with colds and coughs. I wonder if it could be an auto...  Read Full »

Dr. Veerabhadrudu Kuncham

Answer: Hello, Welcome to Every child till 8 years of age has recurring fever episodes due to immature immune systems. Most of the time, a cause cannot be found. Febrile seizures can occur till the age of 6 years. Give a nutritious and balanced diet rich in all foods that enhance the immune s...  Read Full »

I have been suffering from pain, stiffness, and numbness in my joints for three months. Please help.

Query: Hi doctor,I have been suffering from pain, stiffness, and numbness in my joints for three months. My ANA is 30.7 IU/ml, CRP is normal, ESR is 60 mm/hour, and TSH is 11.4 mIU/mL. There is no relief from Duloxetine and Pregabalin.Am I suffering from autoimmunity disease?Thank you.  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to I understand your concern. ANA (antinuclear antibodies) positivity is found in 30 percent of normal people with no significance. Moreover, to your surprise, there are studies claiming that after COVID-19 vaccination, many people are getting ANA positive with no relevan...  Read Full »

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