Autoimmune Disorder

The diseases caused when your body's immune system attacks your body, mistaking it for a foreign body, are called autoimmune diseases. Type 1 diabetes, rheumatoid arthritis, psoriasis, multiple sclerosis, systemic lupus erythematosus, and myasthenia gravis are a few examples of autoimmune diseases. The antinuclear antibody test (ANA) is used to diagnose them.

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Does my symptoms point towards autoimmune disease?

Query: Hello doctor,Based on the following, do I have an autoimmune disease:An overall feeling of sickness.Irregular heartbeat sometimes.Swollen and painful joints.Swollen legs, ankles, fingers, and toes.Headaches sometimes.Shortness of breath.Psoriasis arthritis.Visual problems, burning, itching, very dry...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post. Things which favor the diagnosis of autoimmune disease in your case are as follows: Pain and swelling of joints. Puffiness of hands and feet. Dryness of mouth and eyes. Psoriasis. You need to be investigated for UCTD (undifferentiat...  Read Full »

I have MGUS and elevated levels of free kappa and lambda light chains and immunoglobulins. Should I be worried?

Query: Hello doctor, I have MGUS, and my bone marrow biopsy was taken a couple of years ago. My test results are as follows: free kappa LT chains: 35.2 mg/L, free lambda LT chains: 40.5 mg/L, immunoglobulin results 3,559 mg/L.Should I be worried?  Read Full »

Dr. Sugreev Singh

Answer: Hello, Welcome to Thank you for writing, and I understand your concern. Please send your reports, and I will go through them and let you know. It depends on your symptoms, so please let me know your symptoms. Since when have you been diagnosed with MGUS (monoclonal gammopathy of und...  Read Full »

Why do I have pain in my hand and finger joints?

Query: Hello doctor, I am a 69-year-old male. I have suffered from many types of infections several times in my life from systemic candida infection, valley fever, fungus infections and so on. I also have RA, have experienced Reynauld's several times, I also have SLE and have tested positive for MCTD. I al...  Read Full »

Dr. Mahmoud Ahmed Abdelrahman Abouibrahim

Answer: Hello, Welcome to Repeated infections with different organisms including fungal infection indicate severe immune deficiency which could be due to the steroid therapy you take for MCTD (mixed connective tissue disease) or due to other condition like diabetes. So, please tell me the fo...  Read Full »

Why is there a persistent low-grade fever in a 54-year-old female?

Query: Hello doctor, My mother is 54 years old and is facing persistent low-grade fever. She had it for almost a year and nothing was diagnosed from the tests and then suddenly it got fine. Now again she got a fever from some stomach infection and it has been 15 days that the fever is there between 99 to 1...  Read Full »

Dr. Mukherjee, Koushik

Answer: Hello, Welcome to Did your mother undergo urine culture sensitivity test? Because many of the postmenopausal or perimenopausal women suffer from urinary tract infection that is chronic and drug-resistant due to urinary leak and urinary urgency. Low-grade fever can also be there due to...  Read Full »

I have autoantibodies in my blood and some related specific proteins. What could they indicate?

Query: Hello doctor, I have autoantibodies in my blood and some related specific proteins. I still do not have serious symptoms. I can send my results.  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post and investigations. There are a few significant results in the autoimmune profile. Your ANA (antinuclear antibody), dsDNA (double-stranded deoxyribonucleic acid), and anti-Ro are positive, which is suggestive of SLE (systemic lupus erythemato...  Read Full »

Can Hashimoto's thyroiditis result in high ANA titer?

Query: Hi doctor, I have had an autoimmune reaction for a year now. Symptoms include fatigue, joint and muscle pain, fever spikes (never above 100oF), 40 lbs weight gain in five months, trouble losing weight, swelling, random rashes, heart palpitations, brain fog, migraines, stomach aches, etc. I am curr...  Read Full »

Dr. Sayan Mukherjee

Answer: Hi, Welcome to I understand your concern. Such a high tire ANA (antinuclear antibodies) with centromere positive and musculoskeletal and systemic complaints is usually associated with Sjogren's syndrome, MCTD (mixed connective tissue disease). Concerning your age, it is less likel...  Read Full »

Are my low triglyceride levels due to an autoimmune disease or hyperthyroidism?

Query: Hello doctor, My cardiologist ordered a follow-up lipid test that showed very low TG levels. My follow-up appointment is next week when he will review the results, but I am a bit worried about the low TG levels. I have read that it might be a leading indicator of an autoimmune disease or hyperthyroi...  Read Full »

Dr. Thiyagarajan. T

Answer: Hello, Welcome to I understand your concern. Kindly answer the below questions: Why did you see a cardiologist? Do you follow any specific diet? Do you have any medical conditions? Why was the 24 hours urine iodine checked? Are you on any medications? I suggest you repeat the ...  Read Full »

My daughter has swollen lymph nodes and positive ANA. Please provide opinion.

Query: Hello doctor, My daughter, 15 years, has swollen lymph nodes. Biopsy is done. It is non-malignant. No tuberculosis. But ANA has come positive. I would like to share the reports and take your opinion.  Read Full »

Dr. Naval Mendiratta

Answer: Hello, Welcome to There is a possibility of autoimmune disorder with underlying ANA and large lymph nodes. It is a good thing the malignancy is ruled out. But I would like to see the detailed biopsy report as well to be sure where we are heading. As for ANA positive, I would like to ...  Read Full »

What can be the diagnosis if granulomas are found on pancreas and lungs?

Query: Hello doctor, My husband is 31 years old and has severe anxiety. He was told that granulomas were found on his pancreas and possibly his lungs. They believe it is due to some sort of an autoimmune disorder. Is there anything that can be done to prolong his life? Should we be worried?  Read Full »

Dr. Pratik Patil

Answer: Hello, Welcome to An autoimmune disorder does not necessarily mean his life will be shortened. There arenumerous types of autoimmune diseases which are pathologically neutral and do not endanger life. So, please see a rheumatologist and get him investigated. Regards.   Read Full »

I am suffering from constipation, osteoporosis, and tinnitus. Kindly advise.

Query: Hi doctor, I have not passed stools for the last three and half months. I was given Milk of magnesia a month ago, then laxatives Colace, Miralax, and finally Senna. After taking that, sometimes, little watery stools were passed out. My blood pressure went up from 100 to diastolic 120 sometimes. I al...  Read Full »

Dr. Ajeet Kumar

Answer: Hi, Welcome to As per your description, I think this is a multisystem problem. There is an issue with the muscles, gut, eyes, osteoporosis, and tinnitus. These all can be explained in musculoskeletal disorders or autoimmune disorders like rheumatoid arthritis, systemic lupus erythe...  Read Full »

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