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How to manage autoimmune diseases and migraines?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been dealing with migraines for several years now, and recently, I was also diagnosed with an autoimmune disease. I am not sure if the two are connected, but my symptoms seem to flare up together. When my autoimmune condition worsens, so do my headaches. I have tried various medications for migraine relief, but they either do not work consistently or cause side effects that make my autoimmune symptoms worse. I am also concerned about the long-term effects of being on multiple treatments.

  1. Could the inflammation from the autoimmune disease be triggering my migraines?

  2. Is there a safer, more holistic way to manage both conditions together?

  3. Should I be looking into dietary changes or stress management techniques?

  4. Also, are there specific autoimmune diseases that are commonly linked with migraines?

  5. I would like to understand the underlying connection better. Is it hormonal, neurological, or immune-related?

  6. I am just trying to figure out the right direction for treatment without making either condition worse. What kind of specialist should I see, or is there a clinic that handles both migraine and autoimmune care together?

Please help.

Thank you.

Answered by Dr. Sally Attalah

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I have gone through your query and understand your concern.

Autoimmune diseases can compromise blood-brain barrier integrity, allowing peripheral immune cells and inflammatory mediators to infiltrate the central nervous system and potentially trigger migraine attacks. Such disruption exacerbates neuroinflammation, contributing to migraine pathogenesis.

Common autoimmune disorders linked with migraine,

  1. Rheumatoid arthritis.

  2. Sjögren's disease.

  3. Systemic lupus erythematosus.

  4. Antiphospholipid syndrome.

  5. Multiple sclerosis.

  6. Scleroderma.

Autoimmune disorders often have higher levels of inflammation. So, the goal of the autoimmune protocol (AIP) diet is to choose anti-inflammatory foods and foods that are going to promote gut health to minimize symptoms for people who have chronic immune conditions.

The autoimmune protocol (AIP) is a diet designed to enhance immune regulation, promote gut health, and maintain hormonal balance. Proper implementation of the AIP requires expert guidance, and adverse events remain inadequately understood.

Rheumatologists and endocrinologists both work with patients who have autoimmune conditions.

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.

Medically reviewed by iCliniq medical review team
Published At June 22, 2025
Reviewed At July 17, 2026

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

BDS

Professional Bio:

Dr. Sally Attalah is an experienced Dental Surgeon with a Bachelor of Dental Surgery earned in 2007, followed by her internship in 2008. She has been an affiliate member of the American Dental Association since 2015, reflecting her commitment to maintaining global standards in dental care. Dr. Sally is dedicated to providing high-quality oral healthcare with a patient-focused approach.

This doctor is not available for online consultations on the platform anymore.

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