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Can I get Botox and dermal fillers while on Isotretinoin?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

Can I get Botox or Dysport injections while on Isotretinoin (Accutane)? I would like to receive Botox for my masseter. I would also like to get some dermal filler in my lips. Is it safe to get dermal fillers while on this medication?

Kindly suggest.

Answered by Dr. Akanksha Agarwal

Education:

BHMS

Professional Bio:

Dr. Akanksha Agarwal is a homeopathy specialist with nearly a decade of clinical experience. She focuses on holistic and child-centric care, using gentle, individualized remedies that align with the body’s natural healing. With a strong belief in long-term wellness, Dr. Agarwal helps families manage chronic issues like allergies, digestion, and skin conditions, especially in children, through consistent follow-up and personalized homeopathic planning.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to iCliniq.com.

I read your query and can understand your concern.

Here is a clear and evidence-informed answer regarding cosmetic procedures (like Botox or Dysport (abobotulinumtoxinA) and dermal fillers) while on Isotretinoin (Accutane):

You can safely get Botox or Dysport injections (including masseter Botox) while taking Isotretinoin. These are neuromodulators and work by affecting nerve signals to muscles. Isotretinoin does not interfere with this process and does not increase the risks associated with Botox or Dysport.

No significant contraindications are reported between Botox or Dysport and Isotretinoin. Minimal downtime and no skin trauma are involved in Botox, making it safe even on sensitive skin.

Dermal fillers, while on Isotretinoin, are more complex and somewhat controversial. Historically, it was advised to avoid dermal fillers while on Isotretinoin due to concerns about impaired healing, increased risk of scarring, and inflammation. However, newer studies and expert consensus suggest that hyaluronic acid fillers (like in the lips) may still be safe if proper precautions are taken.

Most dermatologists and aesthetic doctors still prefer to wait three to six months after stopping Isotretinoin before doing dermal fillers, especially in areas like the lips, where healing is delicate.

Some may proceed case-by-case, especially if you are on a low dose of Isotretinoin and have no history of keloid or hypertrophic scarring.

I recommend going ahead with masseter Botox if you wish. For lip fillers, consult your dermatologist or injector, and consider delaying until three to six months after stopping isotretinoin for best safety.

I hope this helps.

Take care.

Regards.

Medically reviewed by iCliniq medical review team
Published At May 30, 2025
Reviewed At May 30, 2025

Education:

BHMS

Professional Bio:

Dr. Akanksha Agarwal is a homeopathy specialist with nearly a decade of clinical experience. She focuses on holistic and child-centric care, using gentle, individualized remedies that align with the body’s natural healing. With a strong belief in long-term wellness, Dr. Agarwal helps families manage chronic issues like allergies, digestion, and skin conditions, especially in children, through consistent follow-up and personalized homeopathic planning.

This doctor is not available for online consultations on the platform anymore.

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Decision Helper
Isotretinoin and Cosmetic Procedures Safety Decision Helper

Considering cosmetic procedures while on isotretinoin?

Answer a few questions to understand the safety of Botox or Dysport injections and dermal fillers while you are taking isotretinoin.

This tool provides educational information only and does not diagnose, treat, or replace professional medical advice. Consult a qualified healthcare professional for personalized medical guidance. Consult your healthcare provider before starting, stopping, or modifying the drugs.

Education:

BHMS

Professional Bio:

Dr. Akanksha Agarwal is a homeopathy specialist with nearly a decade of clinical experience. She focuses on holistic and child-centric care, using gentle, individualized remedies that align with the body’s natural healing. With a strong belief in long-term wellness, Dr. Agarwal helps families manage chronic issues like allergies, digestion, and skin conditions, especially in children, through consistent follow-up and personalized homeopathic planning.

This doctor is not available for online consultations on the platform anymore.

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