Botulinum toxin is a neurotoxin derived from Clostridium botulinum. There are eight distinct antigenic serotypes of exotoxins and among these only A and B are used for various medical indications. Exotoxin A is the most commonly used and it is more potent than exotoxin B.
How does It work?
Botulinum toxin inhibits the release of neurotransmitter (Acetylcholine) at nerve terminal, so it impedes the nerve impulse and leads to paralysis of muscles.
Cosmetic Use of Botox:
Other Uses of Botox:
It is utilized for the treatment of muscle spasm like in torticollis, palmoplantar and axillary hyperhidrosis (excessive sweating).
Preparation of Botox:
Your treating doctor will mix 1 to 2.5 mL of preservative-free normal saline to reconstitute the 100 unit of neurotoxin. This prepared solution can be stored at 2 to 8 degrees Celsius for up to four weeks. Its 0.1 mL contains four units of Botox.
For forehead wrinkles and frown lines use 10 to 25 units, for crow’s feet use 9 to 15 units per side, for bunny lines 3 to 5 units per side, for chin correction use 5 to 15 units and neck bands 20 to 50 units.
The Technique of Injection:
Usually, local anesthesia is not required for cosmetic correction of the face, but in the case of palmoplantar or axillary hyperhidrosis, it is required. The toxin is injected with an insulin syringe, which causes very minimal pain. The needle should be used at 45 degrees to a depth of 2 mm to avoid the back flow of toxin
Instructions to Follow After Procedure:
Side Effects of Botox:
Common side effects are redness, bruising and pain at the injection site. Other side effects include eyelid drooping, eyebrow drooping, ectropion (lower eyelid turn outwards), weakness of hands and deep injection in neck muscles can lead to difficulty in swallowing or bending of the neck.
To know more about botulinum toxin, consult a botulinum toxin therapy specialist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist/botulinum-toxin-therapyLast reviewed at: 07.Sep.2018