Skin and Beauty

Botox - a Toxin with Great Cosmetic Result for Removing Wrinkles

Written by
Dr. Suvash Sahu
and medically reviewed by iCliniq medical review team.

Published on Jan 23, 2017 and last reviewed on Sep 07, 2018   -  2 min read

Abstract

Abstract

Wrinkles on the face are often due to expression, which includes frowning, concentrating or smiling. These wrinkles get deeper as we grew old, because of loss of elasticity of our skin. But, with the administration of Botulinum toxin (Botox) our facial muscles are gently relaxed and the wrinkles improve.

Botox - a Toxin with Great Cosmetic Result for Removing Wrinkles

Botulinum toxin is a neurotoxin derived from Clostridium botulinum. There are eight distinct antigenic serotypes of exotoxins and among these only A and B are used for various medical indications. Exotoxin A is the most commonly used and it is more potent than exotoxin B.

How does It work?

Botulinum toxin inhibits the release of neurotransmitter (Acetylcholine) at nerve terminal, so it impedes the nerve impulse and leads to paralysis of muscles.

Cosmetic Use of Botox:

  • Elimination or cosmetic correction of wrinkles and rhytides on the upper face like crow’s feet wrinkles at the side of our eyes, frown lines or angry lines on the forehead and mid and lower part of the face like the line below eyes, lines around the mouth, chin irregularities and correction of mouth corner.
  • Eyebrow lift - Due to aging if there is a descent of eyebrows, then it can be raised back.
  • Horizontal necklace lines or vertical platysmal band can be corrected.

Other Uses of Botox:

It is utilized for the treatment of muscle spasm like in torticollis, palmoplantar and axillary hyperhidrosis (excessive sweating).

Contraindication:

  • In the case of neuromuscular disorder like myasthenia gravis, autonomic dysfunction, muscle weakness, etc.
  • History of hypersensitivity to this toxin.
  • Local infection at the injection site.
  • Pregnancy and lactation.
  • Individuals on treatment with aminoglycoside antibiotics like Amikacin, Gentamicin, Kanamicin, Neomycin or Spectinomycin, antimalarials, D-Penicillamine and Cyclosporine in the past three days as these drugs accentuate the effects of Botox.

Preparation of Botox:

Your treating doctor will mix 1 to 2.5 mL of preservative-free normal saline to reconstitute the 100 unit of neurotoxin. This prepared solution can be stored at 2 to 8 degrees Celsius for up to four weeks. Its 0.1 mL contains four units of Botox.

Doses:

For forehead wrinkles and frown lines use 10 to 25 units, for crow’s feet use 9 to 15 units per side, for bunny lines 3 to 5 units per side, for chin correction use 5 to 15 units and neck bands 20 to 50 units.

The Technique of Injection:

Usually, local anesthesia is not required for cosmetic correction of the face, but in the case of palmoplantar or axillary hyperhidrosis, it is required. The toxin is injected with an insulin syringe, which causes very minimal pain. The needle should be used at 45 degrees to a depth of 2 mm to avoid the back flow of toxin

Instructions to Follow After Procedure:

  • An individual whom toxin is injected should not recline for 3 to 6 hours to prevent unwanted diffusion of the toxin.
  • Not to massage or manipulate the treated area for 4 hours to avoid bruising.
  • Not to exercise the treated muscles for first 2 to 3 hours like not to frown or raise the eyebrows or smile.
  • Wipe off any toxin immediately if present on the skin.
  • Maximum effects are seen after 7 to 10 days and last for approximately three months and in some cases much longer.

Side Effects of Botox:

Common side effects are redness, bruising and pain at the injection site. Other side effects include eyelid drooping, eyebrow drooping, ectropion (lower eyelid turn outwards), weakness of hands and deep injection in neck muscles can lead to difficulty in swallowing or bending of the neck.

To know more about botulinum toxin, consult a botulinum toxin therapy specialist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist/botulinum-toxin-therapy

Last reviewed at:
07 Sep 2018  -  2 min read

RATING

11
Ask a QueryAsk a Query Consult by PhoneConsult by Phone Video ChatVideo Chat

Tags:

Related Questions & Answers


Do children with soft cleft palate also need multiple surgeries to fix the issue?

Query: Hello doctor, I am having one doubt in my mind. Previously, I read that all cleft palate children usually undergo multiple surgeries. Is this statement valid for the soft cleft palate as well? Children with soft cleft palate also need to undergo multiple surgeries? My child was having only soft cl...  Read Full >>


Dr. Priyanka Aggarwal
Audiologist

Answer: Hello, Welcome to icliniq.com. Multiple surgeries in cleft palate children depend upon the extent of the cleft and the age of the child at the time of operation. Only cleft soft palate rarely need another surgery. But, it is quite often that there is an underlying defect of the hard pal...  Read Full

Is surgery advisable for abductor spasmodic dysphonia?

Query: Hello doctor, I suffer from abductor spasmodic dysphonia diagnosed nearly 11 years ago and I have received Botox injections every three to four months since then. Generally, they did work over the years until the last two years or so outcomes have been very poor. The last Botox shots by GA (six un...  Read Full >>


Dr. Girish Subash
ENT Otolaryngologist

Answer: Hi, Welcome to icliniq.com. First of all, you have to know that among spasmodic dysphonias, abductor variety is the least common type. In this, your vocal cord is away from the other vocal cord and the muscle is in unrestricted contraction resulting in voiceless or breathy voice. So, the treatment...  Read Full

Is injectable Botox safe for a patient with Sjogren's syndrome?

Query: Hi doctor, I am suffering from Sjogren's syndrome. I have a few questions about safety of cosmetic procedures. Is botox injectable safe? Is ultherapy or laser safe for a patient with Sjogren's? Kindly advice.  Read Full >>


Dr. Atishay Bukharia
Cosmetologist, Dermatologist, Family Physician, General Practitioner, HIV AIDS Specialist, Plastic Surgeon, Venereologist

Answer: Hi, Welcome to icliniq.com. Laser is completely safe. Safety of Botox depends on indication. Botox (Botulinum Toxin) is also given in other medical conditions. Please let me know the reason for laser and Botox treatment. The elaborate history will help me to give you better advice. Revert back with...  Read Full

Popular Articles Most Popular Articles

Do you have a question on Cosmetic Procedure or Botox Injections?

Ask a Doctor Online

* guaranteed answer within 4 hours.
Enter Your Health Query
You can upload files and images in the next step.

Fee:  

 


Disclaimer: All health articles published on this website is not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.