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I have HER-2-negative breast cancer. Can it be treated?

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Patient's Query

Hi doctor,

I have been diagnosed with breast cancer, and my test results showed HER2-negative. I am feeling overwhelmed and do not fully understand what this means. Can you explain what HER2-negative breast cancer is, how it differs from other types, and what my treatment options might be? Also, what are the survival rates for this type of cancer?

Thanks.

Answered by Dr. Arshad Hussain Shah

Education:

MD

Professional Bio:

Dr. Arshad Hussain Shah is a Medical Oncologist specializing in the diagnosis and treatment of cancer using chemotherapy, targeted therapy, and immunotherapy. He is dedicated to providing personalized, evidence-based care that supports patients through all stages of cancer treatment while improving their quality of life.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I understand your concern.

Usually, HER2-negative breast cancers are better than HER2-positive breast cancers. Most breast cancers are HER2-negative. HER2-negative means that cancer cells have little to no HER2 protein on their surface. HER2 stands for human epidermal growth factor receptor 2, a protein that helps control cell growth in healthy cells. These types usually have better prognoses.

Hormonal therapy with Tamoxifen blocks the effects of estrogen on hormone receptor-positive breast cancer cells by attaching to the estrogen receptors on the cells. If Tamoxifen is attached to the receptor, estrogen cannot attach to the cancer cell, and the cell does not receive estrogen's signals to grow and multiply.

The survival of patients with this type of cancer depends upon the stage and molecular profile of the patient. In the early stage, or up to stage 3, cancer is curable in most cases with proper treatment. Even stage 4 cancer does well with the treatment in many cases, and life can be extended, and the quality of life can be improved.

I hope this information will help you.

Thanks.

Medically reviewed by Dr. K. Shobana
Published At October 17, 2024
Reviewed At December 8, 2025

Education:

MD

Professional Bio:

Dr. Arshad Hussain Shah is a Medical Oncologist specializing in the diagnosis and treatment of cancer using chemotherapy, targeted therapy, and immunotherapy. He is dedicated to providing personalized, evidence-based care that supports patients through all stages of cancer treatment while improving their quality of life.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Arshad Hussain Shah is a Medical Oncologist specializing in the diagnosis and treatment of cancer using chemotherapy, targeted therapy, and immunotherapy. He is dedicated to providing personalized, evidence-based care that supports patients through all stages of cancer treatment while improving their quality of life.

This doctor is not available for online consultations on the platform anymore.

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