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What causes chronic constipation in a 45-year-old woman?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 45-year-old woman dealing with severe, chronic constipation for over a year. I typically have a bowel movement only every four to five days, and when I do, it is extremely painful with very hard stools. The straining has led to bleeding hemorrhoids and significant discomfort when sitting.

I have tried numerous remedies, such as fiber supplements, prunes, high water intake, regular exercise, and a diet rich in vegetables and whole grains, but nothing has provided consistent relief. I take MiraLAX daily, but it often causes cramping and is not reliably effective.

I feel constantly bloated, my abdomen is distended, and my clothes fit poorly. This issue has become disruptive to my daily life and is affecting my emotional well-being. I also feel embarrassed discussing it, which makes it even harder to cope.

This started around the time I went through menopause, so I am wondering if hormonal changes could be contributing. I also take calcium supplements and antidepressants, both of which I have read can worsen constipation.

My primary care physician suggested it may be dietary, but I am concerned there could be an underlying issue, like a blockage or tumor.

  1. Would you recommend seeing a gastroenterologist?

  2. Could this be a sign of a more serious condition?

Please help.

Thank you.

Answered by Dr. Siphesihle Sokhulu

Education:

MBBS

Professional Bio:

Dr Siphesihle Sokhulu is a General Practitioner who has completed MBBS from the University of KwaZulu Natal in 2021. He has a clinical experience of four years. He treats his patients with atmost kindess and care. He is currently working in VitalCare Medics Inc in South Africa. 

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have read your query and can understand your concern.

I am really sorry to hear how much this has been affecting your daily life. You are absolutely not alone. Chronic constipation is more common than many people realize, and it is completely understandable that you are feeling frustrated and overwhelmed.

Let us go through your situation step by step:

  1. Possible causes of your constipation:

    1. It sounds like you are dealing with chronic constipation, meaning it is persistent and not responding well to standard treatments.

    2. There may be an issue with slow intestinal transit (your bowels move too slowly) or a condition called dyssynergic defecation, where the muscles involved in having a bowel movement do not coordinate properly.

    3. Certain medications, including calcium supplements and antidepressants, are well-known to contribute to constipation.

    4. Hormonal changes during and after menopause can also slow down digestion and worsen symptoms.

  2. Why does this deserve further evaluation?

    1. You have already tried many first-line approaches, such as dietary fiber, hydration, exercise, prunes, and MiraLAX (osmotic laxatives), without consistent relief. That is a strong signal that further medical evaluation is needed.

    2. You should absolutely consider seeing a gastroenterologist, who can:

      1. Perform tests to evaluate bowel function (such as transit studies or anorectal manometry).

      2. Rule out more serious conditions like a bowel obstruction, colonic inertia, or a tumor.

  3. Steps you can take now:

    1. Medication review: Talk to your doctor about:

      1. Adjusting or switching your antidepressant to one with fewer gastrointestinal side effects.

      2. Try a different type or lower dose of calcium supplement that is easier on the gut.

    2. If MiraLAX (osmotic laxatives) causes cramping, ask about alternatives such as:

      1. Stool softeners (for example, Docusate) to reduce straining.

      2. Prokinetic agents or prescription laxatives (for example, Linaclotide, Lubiprostone) that help stimulate bowel movements.

      3. Occasional stimulant laxatives like Senna or Bisacodyl, but only under medical supervision.

  4. Supportive measures at home:

    1. Keep up with hydration and a balanced diet, but be aware that too much fiber without good bowel motility can actually worsen bloating and discomfort.

    2. Use a footstool when on the toilet to improve your posture. It can make bowel movements easier and reduce straining.

    3. Try to avoid straining, as it can worsen hemorrhoids and pelvic floor issues.

    4. Consider pelvic floor physical therapy, which can help if there is dysfunction in the muscles involved in defecation.

  5. When to seek urgent medical attention: Let your doctor know immediately if you experience-

    1. Unexplained weight loss.

    2. Persistent rectal bleeding.

    3. A family history of colon cancer.

Final thoughts

Please know that this is a medical issue, not a personal failure. You have already taken a courageous and important first step by reaching out. Chronic constipation can significantly affect quality of life, but with the right evaluation and treatment plan, things can and do get better.

A gastroenterologist can help you get the answers you need and guide you toward lasting relief, so you can reclaim comfort, confidence, and control over your health.

I hope this answers your query.

Please let me know if I can assist you further.

Thank you.

Medically reviewed by iCliniq medical review team
Published At August 9, 2025
Reviewed At August 25, 2025

Education:

MBBS

Professional Bio:

Dr Siphesihle Sokhulu is a General Practitioner who has completed MBBS from the University of KwaZulu Natal in 2021. He has a clinical experience of four years. He treats his patients with atmost kindess and care. He is currently working in VitalCare Medics Inc in South Africa. 

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr Siphesihle Sokhulu is a General Practitioner who has completed MBBS from the University of KwaZulu Natal in 2021. He has a clinical experience of four years. He treats his patients with atmost kindess and care. He is currently working in VitalCare Medics Inc in South Africa. 

This doctor is not available for online consultations on the platform anymore.

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