Creatine Phosphokinase

Creatine phosphokinase (CPK) is an enzyme present in the heart, brain, and skeletal muscle, which is also known as creatine kinase. It acts as a catalyst in the reaction of producing ADP and phosphocreatine from ATP and creatine. CK-MB is a significant marker of acute myocardial infarction. CPK is raised in conditions like rhabdomyolysis, heart disease, kidney disease, etc.

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What does it mean to have a sudden onset of slurred speech?

Query: Hi doctor, My 70 year old father has developed slurred speech from two days. He has diabetes, benign prostate hypertrophy, and history of vascular dementia. He does not have weakness, paralysis, or numbness. He does not have hypertension or any cardiac disease. He refused to do a CT scan in the ER....  Read Full »


Dr. Hitesh Kumar

Answer: Hello, Welcome to icliniq.com. In a patient, having risk factors, like diabetes mellitus and acute onset slurring of speech, it raises the possibility of developing an acute stroke. Though there may be other causes too. I would suggest undergoing the following tests: MRI of the brain or NCCT (non-...  Read Full »

Can a person having high CPK levels donate blood?

Query: Hi doctor, Can a person with persistent high creatine phosphokinase (CPK) count of 13000 - 17000 IU/L donate blood? Does blood with high CPK count useful for blood transfusion?  Read Full »


Dr. Nagaraj Patil

Answer: Hi, Welcome to icliniq.com. Creatine phosphokinase is an enzyme that is normally present in muscles, heart, brain, etc. Blood donation guidelines do not specify anything related to higher CPK levels and blood transfusion. CPK is released into blood stream following vigorous exercise even in a health...  Read Full »

What does high CPK (creatine phosphokinase) mean?

Query: Hello doctor, I am 25 years old, and my height is 172 centimeters and weight is 68 kilograms. For over a year, I dealt with unexplained symptoms. My condition is constantly fluctuating and sometimes improving. It all started a year ago with bad back pain. After two weeks, I had leg fasciculations t...  Read Full »


Dr. Muhammad Zubayer Alam

Answer: Hi, Welcome to icliniq.com. I can understand your concern. According to your statement, you have been suffering from pain in the buttocks, back of the knees, ankles, and feet, along with paresthesia and some muscle fasciculations. According to your investigation, only raised CPK (creatine phosphok...  Read Full »

Can malaria elevate CPK value?

Query: Hi doctor, My father, who is 70 years old, was admitted in a hospital for severe weakness, high fever (105 degrees Fahrenheit), shivering and lack of appetite. Blood tests revealed that he had malaria (Vivax) and a platelet count of 44,000, which is below normal. But, there was no dengue or typhoid....  Read Full »


Dr. Manish N Garg

Answer: Hi, Welcome to icliniq.com. CPK enzyme (creatine phosphokinase) is specific to the heart. It gets elevated only in cardiac disease and not in malaria. However, a more specific test would be troponin enzyme levels. Also, age does not cause CPK enzymes to increase. Low platelet is due to malaria and n...  Read Full »

CK and ALP test results are attached. What is the name of this disease?

Query: Hello doctor, My 8-year-old nephew is suffering from an unknown disease. We did two tests as suggested by the doctors. The names of the tests are CK and ALP. I am attaching the reports herewith. The doctors suggest that there is no treatment for these diseases. He walks with the help of his toes by...  Read Full »


Dr. M. A. Toyeb, Nazma Parveen

Answer: Hello, Welcome to icliniq.com. I have gone through the attachments (attachment removed to protect patient identity). The symptoms you described and the CPK (creatine phosphokinase) result indicate a muscular dystrophy. Unfortunately, this does not have any cure as of now. I would stil...  Read Full »

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