Could elevated CPK value be related to malaria?

Hi doctor,

My father, who is 70 years old, was admitted to a hospital for severe weakness, high fever (105 degrees Fahrenheit), shivering, and lack of appetite. Blood tests revealed that he had malaria (Vivax) and a platelet count of 44,000, which is below normal. But there was no dengue or typhoid. He had also complained of slight pain in his heart area.

It has only been for the past five days, from the day of the fever. Malaria treatment has already been started in the hospital. For the heart, they did an ECG (an electrocardiogram) and echocardiography, and the results were normal. His doctor said that my father's ECG graph was slightly different from the same one nine years back. Then, they tested for the cardiac enzyme marker CPK (creatine phosphokinase). Apparently, the CPK result should be in the hundreds, but it was in the thousands. So, they are suspecting a heart condition, although they are not sure about the condition.

However, the echocardiogram showed a normal heart without any blocks. They are thinking that at a later stage, they may do an angiogram.

1. Could the elevated CPK value be related to the malaria attack or the treatment of antibiotics for malaria?
2. Could age (70 years) be an issue for high CPK levels?
3. Is an angiogram a must now?
4. Could the platelet count be an indication of heart problems as well as malaria?
5. Are CPK and angiogram tests invasive?
6. Can they be harmful at times?
7. Would you like to state any other general point in the above case?

I have no reports or any other data, so please respond based on the above information. My father has two prior problems. For a few years, he has had prostatitis and slightly low blood pressure.

I hope this helps.

Please revert so I can assist you further.

Thank you.