Q. Could elevated CPK value be related to malaria?

Answered by
Dr. Manish N Garg
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 07, 2016 and last reviewed on: Oct 15, 2020

Hi doctor,

My father, who is 70 years old, was admitted in a hospital for severe weakness, high fever (105 degrees Fahrenheit), shivering and lack of appetite. Blood tests revealed that he had malaria (Vivax) and a platelet count of 44,000, which is below normal. But, there was no dengue or typhoid. He had also complained of slight pain near his heart area. It has been only for the past five days that is from the day of fever. Malaria treatment has been started already in the hospital. For heart, they did an ECG and echocardiography and the results were normal. His doctor said that my father's ECG graph was slightly different than the same 9 years back. Then, they tested for the cardiac enzyme marker CPK. Apparently, the CPK result should be in the hundreds, but it was in the thousands. So, they are suspecting a heart condition, although they are not sure about the condition. But, echocardiogram gave a normal heart without any blocks. They are thinking that at a later stage, they may do an angiogram. Could the elevated CPK value be related to the malaria attack or the treatment antibiotics for malaria? Could age (70 years) be an issue for high CPK level? Is an angiogram must now? Could the platelet count be an indication of heart problems as well as malaria? Are CPK and angiogram tests invasive? Can they be harmful at times? Do you like to state any other general point in the above case? I have no reports or any other data, so please respond on the basis of the above information. My father has two prior problems. Since a few years, he has prostatitis and slightly low blood pressure. Thank you.



Welcome to icliniq.com.

  • CPK enzyme (creatine phosphokinase) is specific to the heart. It gets elevated only in cardiac disease and not in malaria. However, a more specific test would be troponin enzyme levels.
  • Also, age does not cause CPK enzymes to increase.
  • Low platelet is due to malaria and not a heart condition.
  • Yes, angiogram is an invasive test, but with minimal complications. Your father can get a CT coronary angiogram if he wishes for it. It is less invasive than conventional study.
  • I would recommend your father go to for it by seeing the medical condition and raised enzymes. But, it should be done only after he becomes stable after his recovery from malaria.

For further information consult a cardiologist online --> https://www.icliniq.com/ask-a-doctor-online/cardiologist

Was this answer helpful?


Related Questions:
Can you give me a medical opinion on CT angiogram?

.. your CT angiogram images. I need to go through all the images in your CD DVD and will have a detailed look at the vessels near the C1 vertebra area including the jugular veins. Regards. Revert with more information to a radiologist online --> ....   Read full

My daughter has deteriorated coordination after cerebral malaria. Please help.

.. understood your concern about the difficulty in sitting. See due to convulsions and fever of malaria, the brain has gotten some injury due to which she got weakness in the muscles of the body. I advise you to take physiotherapy treatment in the fo...   Read full

Kindly explain the abnormality present in my coronary CT angiogram.

.. here to help you. I have studied your report (attachment removed to protect patient identity). One of your arteries is not following the normal anatomical course as in other people. However, this is a normal variant as is not going to harm you. ...   Read full


This is a sponsored Ad. icliniq or icliniq doctors do not endorse the content in the Ad.

Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

Also Read

What Is Epilepsy Or Seizure Disorder?
We all are familiar with the term epilepsy, and always associate it with fits or seizures. But, there is more to it. So,...  Read more»
Can viral fever lead to Parkinson's disease?
Hello doctor,I had a viral fever six years back. I had a very high temperature of 105, bad cough, also hallucinations. I...  Read more»
Parkinson's Disease: Historical Aspects and Current Treatment Approaches
This article discusses the historical aspects of Parkinsonism and, the evidence based approaches currently available for...  Read more»

Ask your health query to a doctor online?

Ask a Cardiologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.