HomeAnswersMedical Gastroenterologycrohn's diseaseIs Skyrizi effective for managing Crohn's disease?

What are potential impacts of smoking habits while on Skyrizi?

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Published At March 13, 2024
Reviewed AtMarch 13, 2024

Patient's Query

Hi doctor,

I am a 32-year-old man with Crohn's disease, and my doctor prescribed Skyrizi (Risankizumab) for it. I am a bit overwhelmed and have some questions. Could you please explain more about Crohn's disease and how Skyrizi helps in treatment? Are there any specific lifestyle changes I should consider? What potential side effects should I be aware of with Skyrizi, especially considering my recent travels and smoking habits? I smoke 2 cigarettes a day. Will it have an impact?

Hi,

Welcome to icliniq.com.

I do understand your concern.

I would be delighted to offer more information about Crohn's disease and Skyrizi. Crohn's disease is a chronic inflammatory condition affecting the digestive system, causing symptoms like abdominal pain, diarrhea, fatigue, weight loss, and malnutrition. Its exact cause is not fully understood but is believed to involve an immune system response leading to inflammation in the digestive tract. Skyrizi (Risankizumab) is a medication for treating moderate to severe Crohn's disease in adults unresponsive to other treatments like corticosteroids or immunosuppressants. Skyrizi targets a specific protein, interleukin-23 (IL-23), implicated in the inflammatory response in Crohn's disease. By blocking IL-23, Skyrizi reduces inflammation and improves symptoms.

Consider these lifestyle changes:

1. Follow a healthy diet: Consume a fiber-rich, low-fat, and low-sugar diet to manage symptoms. Stay hydrated and avoid trigger foods.

2. Manage stress: Incorporate stress management techniques like meditation, yoga, or deep breathing exercises to reduce inflammation.

3. Get enough sleep: Aim for 7 to 8 hours of sleep per night to manage symptoms and promote overall health.

4. Exercise regularly: Engage in regular exercise, but consult your healthcare provider for any restrictions or modifications based on your condition.

5. Quit smoking:

Smoking worsens Crohn's symptoms; quitting is crucial for managing the disease and overall health.

Potential Skyrizi side effects include:

1. Allergic reactions: Immediate medical attention is necessary if you experience hives, swelling, difficulty breathing, or fainting.

2. Infections: Skyrizi weakens the immune system, increasing infection risk. Discuss recent travel or exposure to illnesses with your healthcare provider before starting treatment.

3. Nervous system disorders: Consult your healthcare provider before starting Skyrizi if you have a history of nervous system disorders.

4. Autoimmune disorders: Skyrizi can elevate the risk of autoimmune disorders. Consult your healthcare provider if you have a history or symptoms of such disorders before starting treatment.

If you have any clarifications, doubts, additional questions, or follow-up inquiries, please feel free to ask again at icliniq website. Wishing you better health.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Vandana Andrews
Dr. Vandana Andrews

General Practitioner

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