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Do I need a new approach for long-term depression?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 43 and have suffered from depression for about 7 years. Depression is still part of my life every day, even though I am on my third antidepressant medication.

I am feeling more and more guilty, and it is getting harder to deal with.

Is this constant feeling of being a burden a normal part of major depressive disorder, or could it be a sign of something else that needs a different kind of help?

Please help.

Thank you.

Answered by Dr. Avinash Choudhary

Education:

MD

Professional Bio:

Dr. Avinash Choudhary is a dedicated psychiatry specialist committed to helping individuals improve their mental and emotional well-being through compassionate, evidence-based care. He has experience in diagnosing and managing a wide range of mental health conditions, including anxiety, depression, stress-related disorders, bipolar disorder, sleep problems, and other psychiatric concerns. Dr. Avinash Choudhary believes in providing a safe, supportive, and confidential environment where patients feel comfortable discussing their concerns. He focuses on personalized treatment plans, patient education, and long-term recovery, helping individuals build resilience and achieve a better quality of life.      

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Thanks for sharing your concerns with us. Thanks for sharing your concerns with us. I have read your question carefully and can understand how upsetting this must be for you. This is especially true if your father has had a good initial response to treatment.

For stage 3B lung cancer, doctors usually give chemotherapy followed by radiation to try to control the tumour in the chest. By the time it is diagnosed, however, there may be tiny cancer cells somewhere else in the body. These cells are typically too small to be seen on scans, and can grow over time, allowing the cancer to spread months after treatment.

Lung cancer often spreads to the spine. Cancer cells can also circulate in the blood and take root in the bones. That does not mean that the previous treatment was useless. Even if treatment controls the primary lung tumour, cancer can still spread to other parts of the body.

There are often no obvious signs that a cancer is spreading. Metastatic disease is when lung cancer has spread to the spine. I am 43 and have been diagnosed with depression for about 7 years.

Depression is still part of my life every day, even though I’m on my third antidepressant. I often have to cancel plans, miss work deadlines, and rely on my wife and kids to do things I normally do myself. And for that reason, I’m more and more guilty, and it’s hard to deal with.

Is this constant feeling of being a burden a common symptom of major depressive disorder, or might it be an indicator of something else that requires a different kind of treatment?

My depression has been around for such a long time and has not gotten much better. Do you think it would be a good idea to go over my treatment plan and make some changes or try something new?

Help me, please.

Thank you.

Medically reviewed by iCliniq medical review team
Published At May 6, 2026
Reviewed At July 21, 2026

Education:

MD

Professional Bio:

Dr. Avinash Choudhary is a dedicated psychiatry specialist committed to helping individuals improve their mental and emotional well-being through compassionate, evidence-based care. He has experience in diagnosing and managing a wide range of mental health conditions, including anxiety, depression, stress-related disorders, bipolar disorder, sleep problems, and other psychiatric concerns. Dr. Avinash Choudhary believes in providing a safe, supportive, and confidential environment where patients feel comfortable discussing their concerns. He focuses on personalized treatment plans, patient education, and long-term recovery, helping individuals build resilience and achieve a better quality of life.      

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Avinash Choudhary is a dedicated psychiatry specialist committed to helping individuals improve their mental and emotional well-being through compassionate, evidence-based care. He has experience in diagnosing and managing a wide range of mental health conditions, including anxiety, depression, stress-related disorders, bipolar disorder, sleep problems, and other psychiatric concerns. Dr. Avinash Choudhary believes in providing a safe, supportive, and confidential environment where patients feel comfortable discussing their concerns. He focuses on personalized treatment plans, patient education, and long-term recovery, helping individuals build resilience and achieve a better quality of life.      

This doctor is not available for online consultations on the platform anymore.

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