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How to treat depression effectively?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I was on Lexapro 20mg for 3 years and decided to come off it because I was feeling good and like myself again. A year later, I crashed hard, and my depression came back. I recently went back on Lexapro in May, and it helped a bit, but not as it used to, I started gaining weight even though I was eating healthy and exercising regularly. I did not notice this the first time I took it because I was not watching my diet or exercising. My doctor switched me to Pristiq (a direct switch from Lexapro 20mg). I have been on 50mg for nearly 5 weeks, and I do not feel any better, if anything, I feel worse. He said it should be working by now and suggested doubling my dose, but I am not sure if I should give it more time. I feel like I might be having withdrawals from Lexapro since I switched immediately without reducing the dose. A second opinion would be appreciated.

Please help.

Thank you.

Answered by Dr. Vipul Chelabhai Prajapati

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

  1. Yes, the sudden switch from 20 mg is not advisable.

  2. So you need to reduce dosage gradually.

  3. But rather I would suggest you need to continue Lexapro 20 mg and then add another antidepressant or mood stabilizer for better improvement.

  4. Lithium Or Bupropion are good options.

  5. With pharmacotherapy start non-pharmacological treatment like exercise and psychotherapy.

  6. Maintain a healthy lifestyle.

  7. Avoid smoking and drinking if any.

  8. Do exercise daily at least 45 min a day.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed by iCliniq medical review team
Published At January 28, 2025
Reviewed At January 28, 2025

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

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