Disease-modifying antirheumatic drugs or DMARDs are used in rheumatoid arthritis patients to slow down the disease process and prevent the gradual destruction of joint tissues by blocking the inflammatory process. There are conventional, targeted, and biologic DMARDs. They suppress the immune system and pose a risk of acquiring infections. Methotrexate, Hydroxychloroquine, Azathioprine, Cyclosporine, etc., are some of the drugs of this group.

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What is the reason for edema of both feet and ankles?

Query: Hello doctor, I am regularly taking 6 oz of warm water with half a slice of a medium-sized lemon and one medium spoon of honey right in the morning for the last 15 days. Whatever be the benefits, I find my arthritic knee pains have slightly increased along with edema of both feet and ankles and pa...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post. You have mentioned that you are suffering from ankylosing spondylitis (AS) with osteoarthritis. But, you have not mentioned which DMARD (disease-modifying antirheumatic drug) you are taking. Anyways, I would suggest the following. NSAIDS (non-...  Read Full »

Do my symptoms of soreness, stiffness and swelling of joints sound like rheumatoid arthritis?

Query: Dear doctor, I have recently had a baby. I experience sore, stiff hands in the morning, swelling, hard bumps on the elbow. There is a history of rheumatoid arthritis in my family. Blood work is negative. Should I go to a rheumatologist?  Read Full »

Dr. Babu Lal Meena

Answer: Hi, Welcome to From your history, it seems that you are suffering fromrheumatoid arthritis. This is more in females, having morning stiffness of the joint and improve during the day and presence of nodules over bony prominences. Yes, you need to go to a rheumatologist for proper eval...  Read Full »

Is it necessary to take DMARDs for psoriatic arthritis?

Query: Hi doctor, I am a 40-year-old female with presumed psoriatic arthritis. At the onset, I had mild, intermittent finger swelling and pain over five years ago, also, intermittent SI joint pain. SI joint X-ray only mentions mild sclerosis. Recent hand X-rays show three small erosions in my fourth and f...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your query. DMARDs (disease-modifying anti-rheumatic drugs) are considered first-line drugs for psoriatic arthritis, especially in patients who are non-responsive to NSAIDs (non-steroidal anti-inflammatory drugs). However, in patients with good responses...  Read Full »

From the reports, please let me know the disease I am suffering from.

Query: Hi doctor, I am a 25 year old male. My height is 5'5" and weight is 55 kg. I am a software engineer. For the last four months, I am having pain in my both hips. To be more precise, the pain is in the front side of the joint between hip and thigh. Around four months back, I had a fall on my right si...  Read Full »

Dr. Akshay Kumar Saxena

Answer: Hello, Welcome to You are very young and should not be having this kind of hip pains that you have described. I have also gone through your reports (attachment removed to protect patient identity), which you have sent and there are some points that we have to concentrate and discuss wit...  Read Full »

I have pain due to RA in spite of taking medicines. Please tell me what I can do.

Query: Hello doctor, I was diagnosed with RA two years back and I am taking treatment for the same. My left knee is affected badly and the swelling is not coming down. Initially, I was not able to walk, but now I can walk slowly but cannot climb the staircase or fold my left leg completely. Recently I am...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post and have seen the reports (attachment removed to protect patient identity). Your rheumatoid arthritis is not controlled which is evident from your high ESR (erythrocyte sedimentation rate) of 60. The reason for this is that you are not adequate...  Read Full »

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