Common "Ena Panel" queries answered by top doctors | iCliniq

Ena Panel

An extractable nuclear antigen (ENA) panel is a blood test that detects autoantibodies in the blood that react with proteins in the cell nucleus. ENA panel typically consists of a group of four or six autoantibody tests. ENA panel testing is used to distinguish and monitor different autoimmune disease progression. In addition, it may be used as follow-up testing to a positive antinuclear antibody (ANA) test to help diagnose an autoimmune disorder.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

My ANA-positive daughter is negative now. Is pregnancy safe?

Query: Hello doctor,My daughter had a little girl four years ago. About three months postpartum, she fell down a flight of stairs injuring her back. At the same time, she had a very bad cold. When her back continued to give her pain after seeing the orthopedist, she went to a neurologist. Her blood work sh...  Read Full »


Dr. Naval Mendiratta

Answer: Hello,Welcome to icliniq.com.Yes, there have been cases where ANA once positive becomes negative towards the later part. Initially, it may have been induced by pregnancy or any infection but over course of time, it becomes negative. As for your friend, I would suggest we do ENA (extractable nuclear ...  Read Full »

What does severe fatigue with positive ANA test indicate?

Query: Hello doctor,I started to become very fatigued. My doctor sent me for some lab work and my ANA tested positive when a high membrane pattern of 1:1280. I have pain in my hands and back of my legs and the fatigue has continued since then. I also developed a bumpy rash on my abdomen. I was put on an an...  Read Full »


Dr. Puri Divya Inder

Answer: Hi,Welcome to icliniq.com.Your test suggests that you are suffering from a connective tissue disease. The symptoms may be nonspecific like you have fatigue, arthritis, rash, dry eyes, and mouth. It is advisable to do an extractable nuclear antigen (ENA) to reveal which particular antibodies are posi...  Read Full »

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