Is erectile dysfunction a side effect of radiation therapy?

Question

Hello doctor,

I am undergoing six months of post-radiation therapy with ongoing erectile dysfunction. I tried Sildenafil without success. PSA is now 0.6 ng/mL. What other treatment options exist for ED? Will vacuum devices or injections affect my cancer treatment?

Please help.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

ED (erectile dysfunction) is a common side effect after radiation therapy for prostate cancer, and there are several treatment options available.

The various treatment options are:

Sildenafil is the first-line therapy but it may not work properly after radiotherapy. Instead, you can use Tadalafil or Vardenafil.
Higher doses or taking these drugs several times a week might improve responsiveness. It is known as penile rehabilitation.
You can use vacuum devices as they are mechanical and do not interfere with cancer treatment.
Drugs like Alprostadil, Papaverine, or Trimix are injected directly into the penis. As they are local treatments, they also do not interfere with cancer treatment. It is also highly effective.
Alprostadil can be used as a suppository, placed in the urethra to deliver it directly to penile tissues. It is less invasive than injections but also less effective.

If all of the above treatments fail, you can go for a penile implant.

Keep monitoring your PSA (prostate specific antigen) level & do not stress. Stress can also be a reason for ED. If you are anxious & stressed, you can visit a psychiatrist.

I hope this has helped you.

Please feel free to reach me again, in case of further queries.

Thank you.