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Should I still use condoms despite a Nexplanon implant?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 26 years old and have been on the implant Nexplanon for over a year now. My periods are irregular, but I do not have any major problems. Do I need to use condoms as a backup if I am on Nexplanon and 26 years old? I know the risk of pregnancy is low, but I am unclear on real-world failure rates.

Do weight or antibiotics affect the implant’s effectiveness? Also, what about STI protection since I am in a new relationship? Sometimes I think every missed period is a failure. Would condoms reduce anxiety, or is it unnecessary medically? I just want to be super safe and informed.

Please help me.

Answered by Dr. Ashraf Ghani

Education:

MD

Professional Bio:

Dr. Ashraf Ghani Niazai is a GMC-certified General Medicine Specialist, recognized by the prestigious General Medical Council (UK). With extensive experience in diagnosing and managing a wide range of acute and chronic health conditions, he combines advanced medical knowledge with genuine compassion for his patients. He is skilled in internal medicine, obstetrics and gynecology, dermatology, preventive healthcare, and lifestyle management, always focusing on personalized, evidence based care to achieve the best possible outcomes. As an inspiring medical educator, he has taught thousands of medical students and contributed multiple research publications to the field of medicine, reflecting his commitment not only to treating patients but also to advancing medical science. Patients value his warm approach, clear communication, and dedication to their long term health and well being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand.

It is totally normal to want some clarity and reassurance here, especially in a new relationship where you are thinking about both pregnancy risk and STI (sexually transmitted infection) protection.

Nexplanon (Etonogestrel) is one of the most effective forms of birth control available. In the real world, the failure rate is well under 1%. This means it is very reliable even with typical use. Irregular or missed periods are very common while using it and do not mean it has failed.

Weight does not make it less effective for most users, and regular antibiotics generally will not affect it. There are only a few rare medications that are of concern, such as some enzyme-inducing drugs.

However, condoms still have an important role in that they are the only method that protects against STIs as well. They are highly recommended in a new relationship until both partners are tested and mutually monogamous.

The implant is already very protective medically, but if you are concerned about pregnancy, then using condoms with the implant can give you extra peace of mind too.

If you are feeling anxious about missed periods, sometimes testing at home can be a simple way to reassure yourself. Overall, you can be assured that the implant is doing its job very well, and condoms add another layer of security and safety in your situation.

I hope you are satisfied with my reply.

Thanks.

Medically reviewed by iCliniq medical review team
Published At June 14, 2026
Reviewed At June 30, 2026

Education:

MD

Professional Bio:

Dr. Ashraf Ghani Niazai is a GMC-certified General Medicine Specialist, recognized by the prestigious General Medical Council (UK). With extensive experience in diagnosing and managing a wide range of acute and chronic health conditions, he combines advanced medical knowledge with genuine compassion for his patients. He is skilled in internal medicine, obstetrics and gynecology, dermatology, preventive healthcare, and lifestyle management, always focusing on personalized, evidence based care to achieve the best possible outcomes. As an inspiring medical educator, he has taught thousands of medical students and contributed multiple research publications to the field of medicine, reflecting his commitment not only to treating patients but also to advancing medical science. Patients value his warm approach, clear communication, and dedication to their long term health and well being.

This doctor is not available for online consultations on the platform anymore.

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Education:

MD

Professional Bio:

Dr. Ashraf Ghani Niazai is a GMC-certified General Medicine Specialist, recognized by the prestigious General Medical Council (UK). With extensive experience in diagnosing and managing a wide range of acute and chronic health conditions, he combines advanced medical knowledge with genuine compassion for his patients. He is skilled in internal medicine, obstetrics and gynecology, dermatology, preventive healthcare, and lifestyle management, always focusing on personalized, evidence based care to achieve the best possible outcomes. As an inspiring medical educator, he has taught thousands of medical students and contributed multiple research publications to the field of medicine, reflecting his commitment not only to treating patients but also to advancing medical science. Patients value his warm approach, clear communication, and dedication to their long term health and well being.

This doctor is not available for online consultations on the platform anymore.

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