Common "Factor V Leiden" queries answered by top doctors | iCliniq

Factor V Leiden

A mutated form of one of the clotting factors is Factor V Leiden. This mutation increases the chance of developing abnormal blood clots, mostly in the legs or lungs. But most people never develop abnormal clots with Factor V Leiden variant.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Will my son’s blood clots seen in the recent scan go away?

Query: Hello doctor, My 28-year-old son, has JME epilepsy, mostly under control and also 1 part Leiden Factor V. He had an accident last year. Broke a few neck bones (Hangman's bone) and broke a few backbones, high up nearer the neck. Son is doing pretty well, and he is walking. He has a total blockage on...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the icliniq.com. The blood clot will not resolve by Aspirin drug. Aspirin is for prophylaxis to prevent further clots formation. For thrombosis, that is a blood clot, and he needs to be prescribed Rivaroxaban or Apixaban like anticoagulant medication. Factor V Leiden mutation put...  Read Full »

Does positive factor V cause heavy bleeding and blood clots?

Query: Hi doctor,My factor V Leiden showed a positive outcome before three months. I got a Depo birth control shot before three months. I have heavy bleeding and blood clots now. Please suggest.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. You have factor V Leiden showing a positive result. So you are at high risk for developing blood clots in various organs of the body especially in the lungs and legs as pulmonary embolism and deep vein thrombosis. If you have major clots occurring in the future, then bl...  Read Full »

A 26-year-old has heterozygous factor V Leiden and DVT. Is Xarelto a safe drug for her?

Query: Hello doctor, My girlfriend is 26 years old and was diagnosed with heterozygous factor V Leiden and heterozygous prothrombin 20210. She is very active, runs half marathons, and works out three to five times a week. She had broken her ankle, and we watched TV for two weeks and noticed some swelling. ...  Read Full »


Dr. Prakash. H. M.

Answer: Hello, Welcome to icliniq.com. Based on your query, my opinion is as follows, 1. Being positive for factor V Leiden and prothrombin is a considerable risk for thrombosis and is very much prone for thrombus formation in the future. This is very much common in homozygous inheritance individuals. 2. I ...  Read Full »

My 17-year-old daughter is on Xarelto for factor V Leiden. Kindly advice.

Query: Hello doctor,My daughter is 17 years old, and she is on Xarelto for four months. Her liver enzymes have gone up. Although it is normal but has increased from the level before drug. Her AST is 43, and the range is up to 31. She is on bcp and has factor V Leiden. This is why her doctor put her on Xare...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the icliniq.com. At this moment I am giving you further information regarding your daughter condition. She has factor V Leiden mutation, which is a congenital cause of thrombosis. So Xarelto (Rivaroxaban) like good anticoagulant drug prescribed to her should be continued. AST (asp...  Read Full »

Is factor V Leiden mutation related to any health issues?

Query: Hello doctor,These are my daughter's bloodwork results that were done nine months back. I was never told about any of these results until I recently asked for copies of her medical record. This year she had irregular and heavy menstrual bleeding and developed a large hemorrhagic ovarian cyst with to...  Read Full »


Dr. Singh Smrita

Answer: Hello, Welcome to icliniq.com. Protein S deficiency causes an increased risk of developing blood clotting disorders mainly thrombosis. It can be hereditary or acquired. Acquired protein S deficiency is seen in liver disease or vitamin K deficiency. Your daughter is heterozygous for factor V Leide...  Read Full »

What is the reason for my feeling weak and numb throughout the day for almost a month?

Query: Hello doctor, I have been feeling weak, numb, and almost passing out throughout the day randomly for a month. I had a CTA in the ER, and they sent me home with this report. And they said to check with neurology, but not to worry. I have read and it says not to worry unless you are symptomatic, which...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. You have hypoplastic right intracranial vertebral and basilar arteries and severe hypoplasia of the right posterior cerebral artery (the P1 segment). But with a patent right posterior communicating artery, which is supplying blood to the right posterior circulation. In my...  Read Full »

What are the precautions needed in pregnant women with Factor V Leiden?

Query: Hi doctor, I am a 23-year old female, and I am unable to ovulate and conceive. I have irregular periods, hormonal imbalance, and I am hard to keep weight under control. I am currently having spotting once or twice a week. I am trying to conceive for one and a half years now. Menstruation started at...  Read Full »


Dr. Sameer Kumar

Answer: Hello, Welcome to icliniq.com. I am keeping in view that you are a diagnosed case of PCOD (polycystic ovarian disorder), hypothyroidism, Factor V Leiden mutation (genetic mutation that causes abnormal clotting), and ADHD (attention deficit hyperactivity disorder). PCOD needs to be addressed first...  Read Full »

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