Common "Hemoglobin F" queries answered by top doctors | iCliniq

Hemoglobin F

Hemoglobin F is the primary carrier of oxygen to the fetus and is also called fetal hemoglobin. It helps in carrying oxygen from the mother's blood to the tissues and organs of the fetus. It is synthesized at the sixth week of pregnancy and continues to be high even after birth until the child is about two to four months old. It is composed of two subunits, namely two alpha and two gamma subunits.

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Is my friend's beta thalassemia screening test seem normal?

Query: Hello doctor,My cousin of 30 years old got tested for beta thalassemia screening test. He got the result as hemoglobin A2 is 2.8 %, hemoglobin F is 0.2 %, and hemoglobin C, D, and S are not detected. Is this normal or has any complications?Please guide.  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The beta-thalassemia screening test appears to be normal. HbA2 levels (hemoglobin A2) are normally between 2 to 3.3% and HbF levels (fetal hemoglobin) are 0.1 to 1.2% for this age. Both are normal. The other hemoglobin typ...  Read Full »

Can sickle cell anemia and beta thalassemia occur together?

Query: Hi doctor, My friend is 26 years old. He has sickle cell anemia and thalassemia together. His recent spleen health was good and the proportion of blood and iron was moderate. He does not need to increase the blood. Is it rare to see these two together? What is the average life expectancy of these p...  Read Full »


Dr. Veerendra Channabasappa Patil

Answer: Hello, Welcome to icliniq.com. As per your description, your friend seems to be having sickle beta-thalassemia. It is common to see both these diseases together in communities where both diseases are prevailing. Actually, the severity of sickle cell disease comes down by the elevation of the Hb...  Read Full »

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