Hemolysis is defined as the red blood cell destruction that may be due to various causes due to which hemoglobin is released into the bloodstream. The etiology behind hemolysis includes hemolytic anemia, artificial heart valves, bacterial infection, hemodialysis, HELPP syndrome, coronary bypass, overactive spleen, hereditary elliptocytosis and spherocytosis, malignant hypertension, thrombotic thrombocytopenic purpura, transfusion reaction, medications, Wiscott-Aldridge syndrome, etc.

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I have been experiencing weakness and tiredness recently and my blood vitamin B 12 level is 96.4 pg/mL. Is this normal?

Query: Hello doctor, I feel weak and tired today after undergoing a blood test, and my vitamin B12 level is 96.4 pg/mL. What should I do? Also I am a vegetarian. Please help.  Read Full »

Dr. Basuki Nath Bhagat

Answer: Hello, Welcome to icliniq.com. I have read your query and understand your concern. Let me to download your laboratory report and respond to you afterward. 26.Mar.2023 01:31am: Your lab report Vitamin B12 is low 96.5, homocysteine is high, folate is normal CBC is normal HbA1c, Thyroid profile test a...  Read Full »

My six-month-old son has been diagnosed with G6PD deficiency. Please help me understand his disease stage, dietary restrictions, and risk of infection in hemolysis.

Query: Hi doctor, My son is six months old and has been identified with G6PD deficiency. His hemoglobin levels are 0.92 gm/dL. I want to know whether the deficiency is mild, moderate, or severe. As I read, 10 to 60 percent of the levels are moderate. Also, I have heard legumes are restricted. We have a pul...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I went through your query and understood your concern. To classify G6PD (glucose-6-phosphate dehydrogenase) deficiency, clinical hemolytic episodes and hyperbilirubinemia also need to be considered. If there is a continuous hemolysis attack and due to that hemoglobi...  Read Full »

Please review my LFT, and let me know if my liver is healthy.

Query: Hi doctor, A couple of weeks back, I took the a few blood tests that I have attached due to a bacterial food infection. I am fine now after the course of antibiotics. I would like to know whether my liver is healthy. Please review my LFT and advise whether my liver is fine. Please prescribe medicati...  Read Full »

Dr. Basuki Nath Bhagat

Answer: Hello, Welcome to icliniq.com. I saw the report you have attached (attachment removed to protect patient identity). Sorry for your discomfort. Your liver enzymes that is SGOT (aspartate transaminase), SGPT (alanine transaminase), alkaline phosphatase and GGT (gamma-glutayl transferase) are normal....  Read Full »

Can you please confirm my friend's diagnosis?

Query: Hi doctor, I am a general practitioner. I would like to consult with you regarding my friend, who has a normochromic normocytic anemia. His hemoglobin is currently 7.5. His diagnosis is not clear. I have all his laboratory data and bone marrow biopsy as well as aspiration if you want. He used to tak...  Read Full »

Dr. Sadaf Mustafa

Answer: Hello, Welcome to icliniq.com. One thing for sure is that he is having periodic hemolysis with adequate bone marrow response and he has a severe vitamin B12 deficiency. His corrected RPI (reticulocyte production index) is 2.7%, which means that his bone marrow is responding to the anemia ...  Read Full »

What is the reason for change in liver function tests? Taking Concor 5 mg for High BP.

Query: Hi doctor, I am a 45 year old male. I have recently checked my blood test and my liver function test shows 1.6 total bilirubin, 0.6 direct bilirubin and 0.9 indirect bilirubin. What might be the problem? I have high blood pressure and fatty liver. My current medication includes Covance 25 mg, Conco...  Read Full »

Dr. Abhishek Kirti Dixit

Answer: Hi, Welcome to icliniq.com. Considering your indirect bilirubin being high (attachment removed to protect patient identity), it is generally a sign of hemolysis (breakdown of red blood cells). Did you have a recent fever? You also have fatty liver, which may also cause this. I would suggest you ...  Read Full »

Why is my bilirubin level a bit higher?

Query: Hello doctor, I am a 29-year-old male, weigh 90 kg, height is 182, non-smoker, non-alcohol drinker. I do not have any symptoms or signs, normal eye, and skin color. I am taking Cipralex 15 mg for the past one year. Had a history of bladder stone and it required admission for one week until it passe...  Read Full »

Dr. Babu Lal Meena

Answer: Hi, Welcome to icliniq.com. If Mmol means micron mol, then it is fine (attachment removed to protect patient identity). It looks like a normal variant of hyperbilirubinemia. Most common cause of the condition is hemolysis, Gilbert syndrome is also a common cause of such a situation. In both the co...  Read Full »

Why does my hemoglobin level remain the same with blood infusion?

Query: Hello doctor, My hemoglobin level is low. My ferritin level is at high 959.7 mg/ml. My hemoglobin levels is same even after taking three units of blood in the last month. It is still 6 g/dl. Last month my is ESR 32 and now it is 110, platelet count 128000 last month and now it is 60000, WBC count 43...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I have read your reports (attachment removed to protect patient identity), and following is my opinion for your asked question. In your attached report, reticulocyte count and bilirubin level are high. Ferritin is also high. Liver and spleen enlarged in USG (ultra...  Read Full »

Mine and my wife's blood group is B. Will it cause any problem in our married life?

Query: Hello¬†doctor, My wife's and mine blood groups are the same. Both of our blood group is B. Will there be any problem in our married life?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. There are two major blood group systems. ABO - According to this system, the blood group can be A, B, O, AB.  Rh system - According to this system, the blood group can be Rh positive or negative. You have not mentioned th...  Read Full »

Can you see the attached CBC report, and let me know if there is anything serious ?

Query: Hi doctor, My wife's iron and ferritin were low, so the doctor ordered CBC. CBC showed low WBC, high monocytes, and high RBC, which is what made us scared. She has schistocytes and elliptocytes among other RBC morphologies. We read about it and are very worried, and she had a C-section three years...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I have gone through your wife's reports (attachment removed to protect patient identity). The report shows schistocytes, which are fragmented RBC (red blood cell), commonly seen in hemolytic anemia. So, to rule out hemolysis, serum LDH (lactate dehydrogenase), ret...  Read Full »

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