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Can antipsychotics cause hormonal imbalance in women?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My friend’s ex-girlfriend is 35 and has paranoid schizophrenia. She stopped her antipsychotic medicines a few months ago because she said they were making her gain weight and killing her libido. She is now showing signs of relapse. Are there newer medications with fewer sexual and hormonal side effects for women? She also has irregular periods and facial hair. Could her medication or condition be linked to PCOS?

Thanks.

Hi,

Welcome to icliniq.com.

I can understand your concern.

I am sorry to hear about the difficulties your friend's ex-girlfriend is facing. It is possible that her antipsychotic medications were contributing to weight gain and libido issues, which can be common side effects. There are newer antipsychotic medications that may have fewer sexual and hormonal side effects, such as Aripiprazole and Lurasidone. These medications might be worth discussing with her healthcare provider. Irregular periods and facial hair can be symptoms of PCOS (polycystic ovarian syndrome), which is a hormonal disorder. It is possible that her condition or medications could be linked to PCOS. She needs to consult with her healthcare provider to discuss her symptoms and explore treatment options that address both her mental health and hormonal issues. Please book a consultation with me if you would like more detailed information.

I hope this information will help you.

Thanks.

Medically reviewed byiCliniq medical review team

Published At August 9, 2025
Reviewed AtAugust 21, 2025

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