I have hypertension and also suffer from asthma. I have been prescribed ARBs. However, I have experienced respiratory side effects (dyspnea) that lead me to discontinue the medication. The side effects are class effect and all drugs from this class will have these effects. I cannot use ACE Inhibitors or ARBs or beta blockers due to asthma. I can only use CCBs and/or diuretics. Regarding CCBs, I have tried Amlodipine but felt much fatigue, then Nifedipine XL that caused intolerable headaches. Then I have been suggested to use Felodipine but it is not available in my country. Finally, I have been prescribed Dilzetem 90 mg BID and low dose Hydrochlorothiazide (12.5 mg). However, I can no longer take HCTZ because it causes me severe sciatica. In my country, the medication Clortalidone is not available. What should I take instead of HCTZ? The Diltiazem alone cannot help me. My current blood pressure shows 150/95 mmHg and pulse rate 87 beats per minute. Should the dose of Diltiazem be adjusted? Or perhaps another medication should be added? Thank you.
I have reviewed your health query and can understand your worries about hypertension and appropriate medications. Although thorough physical evaluation is mandatory here, I would assist you based on the details provided here. I would suggest you start afresh with lifestyle changes and medications together. You need to get your BMI within normal limits. Every 10 pounds you lose will lower your blood pressure by 5 mmHg. Meanwhile, you need to consult a dietitian to fix your diet according to the healthy lifestyle. You need to take your weight and lipids (cholesterol) within limits via lifestyle changes. I am sure you can do this but it needs a lot of serious efforts. All medications would then depend on your efforts. If you take control of your weight and cholesterol, you would not need much of medications to lower your blood pressure. Yes, if needed your physician can alter the dosage of Diltiazem according to it until you get your blood pressure within normal limits. Hope it helps. Thank you.
Thanks for your response. I suffer from depression, anxiety, and insomnia. I am currently taking medication for mental illness. Two of them are known to increase body weight through increasing appetite and slowing metabolism. However, I know I need to lose weight urgently and I am willing to visit a dietician and make all the necessary efforts. Regarding the medication, I would like to ask you specifically about Diltiazem. I am currently taking 90 mg twice a day, and I think it is already a high dose. Unfortunately, since I stopped hydrochlorothiazide my blood pressure went higher again. What should I do regarding the medication? Should I take more doses of Diltiazem? What risks would I face in case I take 120 mg twice daily? Thank you.
Yes, it would be really helpful for you to consult a dietician as you need to work on this issue in depth and get a prescription renewal. Diltiazem 90 mg twice is high but not the highest limit you may take in a day. You may consult your treating physician for proper guidance and to see how can they titrate the dose according to your needs. It can safely be increased in many patients. Many patients take more than 120 dosages per day and there is no issue (480 to 540 mg per day is mostly the limit in hypertension). Your doctor may titrate it over a couple of weeks and see how it works. But, again this all depends on your physician's evaluation. Hope this helps. Thank you.
Was this answer helpful?
Same symptoms doesn’t mean you have the same problem. Consult a doctor now!
.. ED (erectile dysfunction), definitely your age can be a factor. But, if ED developed suddenly, then this could be caused by anxiety. It is one of the most important causes of ED.
Yes, some ARBs (angiotensin receptor blockers) can cause ED as a side eff Read full
.. you must have undergone echo in order to find out the cause of atrial fibrillation.
Now, regarding your doubt, as such the risk of stroke is not high in you so blood thinners are not absolutely necessary for you. Read full
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.