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HomeAnswersInternal MedicineinfertilityI am unable to conceive. Please help.

Can tubal blockage cause infertility?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

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Published At May 25, 2018
Reviewed AtFebruary 7, 2024

Patient's Query

Hi doctor,

I am 33 years old. For the past six months I am suffering from primary infertility, PCOS and diagnostic laparoscopy tubal block at right isthmus. Also, laboratory tests like Mantoux (positive), HBsAg (positive), ANA (positive) and LFT raised tests are done. The IUI done twice and my current medication is Metformin and Folic acid. Please suggest me.

Hello,

Welcome to icliniq.com. Tubal blockage or fallopian tube obstruction is a major cause of female infertility. Blocked fallopian tubes will not let a sperm and ovum to unite thus interfering with fertilization.The primary and the very first step for pregnancy is the formation of zygote followed by embryo and its implantation. This step is interrupted in tubal blockage.

Have you undergone a tubal patency test? Have you ever had an ammonia tolerance test (ATT)? Do you have a history of laparoscopy and chromotubation? The cause of tubal blockage can vary. It could be due to conditions like genital tuberculosis, endometriosis, or pelvic adhesions. It is important to determine whether the blockage is unilateral or bilateral. If both tubes are blocked, intrauterine insemination (IUI) may not be effective, and in vitro fertilization (IVF) is recommended. Before proceeding with IVF, it is advisable to undergo a hormonal profile test, including D2 or D3 luteinizing hormone (LH), follicle-stimulating hormone, estradiol, prolactin, AMH (anti-mullerian hormone), and a thyroid profile. IVF involves steps such as oocyte retrieval, sperm collection, in vitro fertilization, and embryo transfer.

Concerning your HBsAg positive status, the transmission to the baby can be prevented by administering Hepatitis B immune globulin (HBIG) and Hepatitis B virus (HBV) vaccination soon after delivery. Elevated liver function test (LFT) results are a concern as they may indicate acute viral hepatitis. It is advisable to undergo tests for HBeAg, HBV DNA, and anti HBcAg (hepatitis B core antigen) to assess viral replication. Being ANA (antinuclear antibody test) positive may contribute to pregnancy difficulties such as miscarriages due to immune rejection. In such cases, immunosuppressive therapy with steroids and progesterone suppositories may be recommended.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Geetha Priyadarsini Kamminana
Dr. Geetha Priyadarsini Kamminana

Internal Medicine

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