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Does insulin resistance make body tired and dizzy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 35-year-old woman weighing 207.23 pounds with a BMI of 34. I have been struggling to lose weight despite trying diets and walking. My blood reports show borderline insulin resistance and high triglycerides. I have irregular periods and was told I might have PCOS.

I have also tried to conceive for the past year without success, and my doctor said weight could be a major reason. I am considering medications like Semaglutide or even bariatric surgery, but I am not sure what is safer since I want to get pregnant later. Could these drugs affect fertility or harm the baby if I conceive while on them?

Would weight loss improve my hormone levels and chances of ovulation naturally? Also, are there specific exercises or foods that can help reduce abdominal fat faster? I sometimes feel tired and dizzy. Could that be due to insulin resistance or hormonal imbalance?

Please help.

Thank you.

Hello,

Welcome to icliniq.com.

I can understand your concern.

Well, lots of queries, so let us go through them one by one. Everything you have described fits into a hormonal–metabolic pattern that we see very often, and it responds well once we tackle insulin resistance in a systematic way.

Before we fine-tune your plan, could you please tell me your latest HbA1c value and when it was last checked? That single number helps me see how much your insulin resistance is affecting glucose control and whether we should start formal diabetes prevention treatment.

I would also like to know your thyroid profile, vitamin D, vitamin B12, and lipid panel results, if you have them, because deficiencies or thyroid imbalance can worsen weight gain and fatigue.

With a BMI (body-mass index) of 34, your goal should be an initial five to 10 percent weight loss over the next few months. That alone can significantly improve ovulation, reduce androgen levels, and lower triglycerides. Many women start getting regular periods and even conceive naturally once that happens.

From a medication standpoint, Metformin remains the safest and most established option. It improves insulin sensitivity, helps regulate cycles, and can be continued when pregnancy occurs. Drugs such as Semaglutide are very effective for weight loss and can dramatically improve insulin resistance, too, but they are not to be used during pregnancy.

If weight has remained resistant despite medical therapy and lifestyle measures, bariatric (metabolic) surgery can be discussed. It leads to substantial and sustained weight loss and often restores fertility in women with PCOS (polycystic ovary syndrome). Pregnancy should, however, be postponed for about 12 to 18 months after surgery, and careful nutritional supplementation is needed throughout that period.

Your tiredness and dizziness can be due to fluctuating sugars from insulin resistance, low iron or vitamin B12, thyroid imbalance, or low caloric intake. We should confirm this with the basic laboratory tests mentioned earlier. Correcting even mild deficiencies can greatly improve energy and metabolism.

For diet, aim for a gentle calorie deficit- about 500 to 700 kcal less than your maintenance intake. Include protein at every meal, plenty of fiber, vegetables, legumes, and avoid refined carbohydrates and sugary foods. Alcohol and sweetened drinks are major contributors to high triglycerides and should be minimized.

In terms of exercise, the combination of 150 to 300 minutes of moderate-intensity aerobic activity per week (such as brisk walking, cycling, or swimming) and two or three strength-training sessions is ideal. Building muscle helps burn abdominal fat and improves insulin sensitivity more than cardio alone. Adequate sleep (seven to eight hours) and stress-reduction techniques such as yoga or meditation also have a measurable impact on insulin levels.

We will keep a close watch on your blood pressure, lipid profile, and glucose every few months. If triglycerides remain high despite weight loss, we can consider omega-3 supplements or specific triglyceride-lowering therapy, but most women see major improvement once diet and insulin sensitivity are corrected.

I hope this information will help you.

Kindly follow up if you have any further concerns.

Thank you.

Medically reviewed byiCliniq medical review team

Published At March 26, 2026
Reviewed AtMarch 27, 2026

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