Insulin Resistance

The hormone insulin regulates the cells in the pancreas to absorb and use glucose. Insulin resistance makes the pancreatic cells resistant to insulin, making them unable to metabolize glucose. The risk factors for developing insulin resistance are obesity, sedentary lifestyle, smoking, hypertension, and sleep problems.

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Last week I had an episode of shaking, sweating, and weakness due to hypoglycemia. What to do?

Query: Hello doctor, I have had reactive hypoglycemia for one and a half years. I am taking the medication Synthroid 100 mcg, and I do not take any medication for hypoglycemia. I am usually pretty good at keeping it stable by eating small meals throughout the day. Last week I had an episode of shaking, swe...  Read Full »


Dr. Thiyagarajan. T

Answer: Hello, Welcome to icliniq.com. Yes, it is possible. You probably have insulin resistance, and as a result, more insulin production after a meal leads to hypoglycemia. I would suggest the following: 1. Get your fasting and postprandial glucose and insulin levels checked. 2. Weight loss will help....  Read Full »

Why is my postprandial blood sugar 209?

Query: Dear Doctor, My blood sugar report says that I have readings of Fasting Blood Sugar: 145 and Postprandial Blood Sugar: 209. I am on insulin. Please advise me as early as possible.  Read Full »


Dr. Rohit Jain

Answer: Hi, Welcome to icliniq.com. You don't need to panic. This is not something serious. For a good effective treatment, I need to know what medicines you are taking along with insulin. Also, there are 100 kinds of insulin, which one are you currently taking and in what dose. It might be just cured with ...  Read Full »

Can bariatric surgery be repeated?

Query: Hi doctor, I am 41 years old. I am suffering from hypothyroidism and for which I am taking Thyroxine 175 mcg daily. My height is 5 feet and 10 inches, and my current weight is 127 kg. Two years ago, I had a sleeve gastrectomy and lost only 20 kg. The surgeon now advised me to get gastric bypass sur...  Read Full »


Dr. Divakara P

Answer: Hi, Welcome to icliniq.com. I went through your query and the reports (attachment removed to protect identity). Your testosterone level is normal. Though on the lower side of the normal range, nothing needs to be done to increase testosterone. There are medications to increase testosterone lev...  Read Full »

How to reduce pain produced around the Insulin injection site?

Query: Hi doctor, I am suffering from type 1 diabetes. My HbA1c is too high. I have been on Insulin for around seven years now, and I am trying to lower it. I have a few questions. I keep getting Insulin bumps and lumps every time I choose the abdomen for an injection site. How can I ensure adequate insuli...  Read Full »


Dr. Krutika Shrikant Ingle

Answer: Hello,Welcome to icliniq.com.Let us go step wise just like your concerns.The best way for avoiding lumps, bumps, and pain due to repeated Insulin injections is by learning the proper technique for injecting yourself. Please meet a local doctor to learn the same.Also, keep changing the injection site...  Read Full »

Is darkness in the neck and armpit indicative of insulin resistance in a child?

Query: Hi doctor, My daughter is going to be 8-year-old in two months. I doubt that she has Insulin resistance. Her height and weight are more. She has darkness at her neck, armpits, etc. She is getting a lot of hair on her body. What can I do about that? Please guide me.  Read Full »


Dr. Dhepe Snehal Laul

Answer: Hi, Welcome to icliniq.com. Is there any hormonal imbalance or fluctuations? Does she have stress, anxiety, worries, or phobia? Is she on any drug therapy? Is she good at her studies? Is she mentally stable? Is there any family history of diabetes? Please answer the above questions so that I can ...  Read Full »

How to differentiate between hormonal imbalance or insulin resistance?

Query: Hi doctor,I am 22 years old. I am struggling with a problem of weight gain for three years now. I took a birth control pill and stopped it this year. My weight has got increased up to 16 kilograms in these three years. I urinate every 30 to 60 minutes. I have a puffy round face. I have tried dieting...  Read Full »


Dr. Afifa Nighat

Answer: Hi, Welcome to icliniq.com. Insulin resistance occurs commonly in obese patients resulting in a diagnosis of metabolic syndrome. There is a subnormal glucose response to the endogenous or exogenously administered insulin. This defines insulin resistance. In your case, it is necessary to rule out p...  Read Full »

Is there a cure for dark skin around the pubic region?

Query: Hello doctor, I am a 20 year old male. I have type 1 diabetes for the past seven years. I am using Insulin pump with Novo Rapid insulin for 4 years now. From the past six months, the skin around my pubic region is becoming dark. It is not itchy, but it is dark compared to the whole body complexion...  Read Full »


Dr. Rakesh Kumar Bahunuthula

Answer: Hi, Welcome to icliniq.com. Hyperpigmentation in the body folds and groin region is a commonly seen problem in people with diabetes and insulin resistance. It is usually a consequence of excess weight, which leads to such changes. Also, the addition of friction in these areas increases the problem ...  Read Full »

Please suggest ways to regularize my menstrual cycle with PCOS.

Query: Hi doctor, I am 23 years old. I am really worried and fed up with my fat thighs and hips. As I am suffering from polycystic ovarian syndrome and I used to miss my menses. Now, my menstruation is regular. But, whenever I skip physical exercise I am sure that I will miss my menses. I think these all...  Read Full »


Dr. Sameer Kumar

Answer: Hi, Welcome to icliniq.com. As you are a case of PCOS (polycystic ovarian syndrome), which brings obesity and insulin resistance along with it. Consult a doctor for medical advice to lose weight and improve insulin resistance to allow regular menses to occur. Also it is important to maintai...  Read Full »

Please suggest a way to increase leptin sensitivity.

Query: Hi doctor, I am a 19 year old female. How to increase my leptin sensitivity to increase my metabolism? After losing 12 kg, now I am gaining weight easily. Also, my shape gets ruined as I am gaining weight in the wrong place. Please help.  Read Full »


Dr. Uphar Gupta

Answer: Hi, Welcome to icliniq.com. You need to lose weight to increase your leptin sensitivity. In general, insulin resistance generates leptin resistance. It means one should not let the insulin level to go up. Sugar makes insulin go up and we are overdosed with sugar in this country. If we get the sugar ...  Read Full »

Can a hypothyroid patient develop diabetes?

Query: Hello doctor, I am hypothyroid. Thyroid gland destroyed by Radioactive Iodine 14 years ago. My fasting blood sugar level is always in the range of 6.1 to 6.5. I have tried intermittent fasting even after 22 hours it does not drop below 6.0. Postprandial is in the range of 9.5-10.4. I do not have an...  Read Full »


Dr. Nadeem Abootty

Answer: Hi, Welcome to icliniq.com. From your history it is evident that you are on replacement therapy for hypothyroidism post-radioactive iodine,and also known diabetic since 6 months. From your history, age and other parameters it is type 2 diabetes mellitus. It is not only carbohydrates which contribu...  Read Full »

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