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What are the treatments available for IBS-D?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am really worried about my father’s second wife. She has terrible IBS-D, and it is tearing their marriage apart. She is 50 and has always been healthy, but this started after a bad bout of food poisoning last year. Now, she can barely leave the house. My dad is doing all the shopping, cooking, everything. She has tried probiotics, fiber supplements, and even some herbal stuff, but nothing helps. She is depressed and talks about divorce to 'free' my dad. He loves her but is exhausted. They can not travel or go out anymore. Is there any hope? What about fecal transplants? Are they safe?

Please help.

Hello,

Welcome to icliniq.com.

Understandably, your dad is feeling overwhelmed with caregiving, significantly, as her condition affects their daily activities and social life.

Given that her IBS-D (irritable bowel syndrome with diarrhea) symptoms began after a severe bout of food poisoning, she may be experiencing a condition known as post-infectious IBS, which can occur in some individuals after gastrointestinal infections.

The treatment plan options can be -

  1. Medications specifically for IBS-D, such as Eluxadoline or Rifaximin, target symptoms more effectively than general probiotics or fiber supplements.
  2. Cognitive behavioral therapy (CBT) has also shown promise in helping manage IBS symptoms by addressing the stress and anxiety that can accompany the condition.

Fecal microbiota transplantation (FMT) is a procedure that involves

  1. Transferring stool from a healthy donor to the patient to restore gut microbiome balance.

  2. While it has been effective for certain conditions, such as Clostridium difficile infection, its efficacy in IBS is still being studied.
  3. FMT is generally considered safe but should only be pursued under the guidance of a healthcare professional in a controlled setting, as the long-term effects and risks need to be carefully evaluated.

Encouraging her to seek comprehensive care, which may include dietitians, therapists, and specialists, could provide her with a better support system and help improve her symptoms.

There is hope for managing IBS-D, and with the right treatment plan, she may find some relief, helping to rebuild her quality of life and, in turn, strengthen their marriage.

I hope this helps.

Thank you.

Medically reviewed byiCliniq medical review team

Published At October 25, 2024
Reviewed AtNovember 11, 2025

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