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What can be the reason for lower leg swelling?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am a healthy and active 18-year-old female. I have swelling in my right calf or lower leg when sitting. There is no foot swelling. The swelling is present in the calf and it goes away within an hour if I move around. I do have night sweats. I get easily bruised and feel constant cold and fatigue. I was ruled out for circulation problems and varicose veins. My blood tests show a positive ANA, slightly low WBC and RBC, and slight anemia. This leg swelling has been happening for the last two months.

Kindly help.

Answered by Dr. Sagar Ramesh Makode

Education:

MBBS

Professional Bio:

Dr. Sagar Ramesh Makode is a Consultant Cardiologist dedicated to diagnosing and managing various heart conditions with precision and care. He focuses on improving cardiovascular health through advanced treatments and preventive strategies. With expertise in providing personalized care, he strives to support patients in achieving better heart health, enhancing their quality of life, and reducing the risk of future cardiac complications.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

The swelling can be attributed to either venous or lymphatic reasons. Assuming you've undergone a venous Doppler for deep vein thrombosis and the results were normal, the remaining consideration is a lymphatic cause. To further explore this, it's recommended to undergo lymphoscintigraphy and thyroid testing.

Meanwhile, reducing salt intake is advised. Given the positive ANA (antinuclear antibody) mentioned, it's important to also undergo testing for anti-dsDNA. This evaluation is crucial for assessing the potential presence of systemic lupus erythematosus (SLE).

Additionally, investigating the cause of anemia, which can exacerbate swelling, involves obtaining vitamin B12, folic acid, and iron studies. To alleviate the swelling, consider placing a pillow under your legs during sleep. Consulting a medical professional for these evaluations is essential for accurate diagnosis and appropriate management.

I hope this helps.

Thank you.

Medically reviewed by iCliniq medical review team
Published At January 12, 2017
Reviewed At May 8, 2026

Education:

MBBS

Professional Bio:

Dr. Sagar Ramesh Makode is a Consultant Cardiologist dedicated to diagnosing and managing various heart conditions with precision and care. He focuses on improving cardiovascular health through advanced treatments and preventive strategies. With expertise in providing personalized care, he strives to support patients in achieving better heart health, enhancing their quality of life, and reducing the risk of future cardiac complications.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Sagar Ramesh Makode is a Consultant Cardiologist dedicated to diagnosing and managing various heart conditions with precision and care. He focuses on improving cardiovascular health through advanced treatments and preventive strategies. With expertise in providing personalized care, he strives to support patients in achieving better heart health, enhancing their quality of life, and reducing the risk of future cardiac complications.

This doctor is not available for online consultations on the platform anymore.

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