Liver Biopsy

The procedure of retrieving a small piece of liver tissue to diagnose the cause of enlarged liver, prolonged abnormal liver enzyme levels, chronic jaundice, alcoholic liver disease, nonalcoholic fatty liver, primary biliary cirrhosis, etc., is known as liver biopsy test. The risk of internal bleeding is present. A needle can be directly inserted into the abdomen (percutaneous), or a small incision on the stomach can be made, and tissue can be retrieved laparoscopically, or a thin tube can be introduced into the jugular vein through a neck incision, and liver tissue can be retrieved.

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Please help me understand the liver biopsy of a diabetic patient.

Query: Hello doctor, Below is the biopsy report of my father who is 72-year-old diabetic. He was not feeling well for past one month. Can you please help me understand what does it mean? The liver biopsy result states that: Gross: Linear cores of tissue largest measuring 1 cm-A/E (pJA/SH). Microscopy: sh...  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to I am very afraid to tell you that these reports (attachment removed to protect patient identity) are suggestive of liver cancer. This needs to be evaluated by further CECT (contrast-enhanced computed tomography) abdomen and PET (positron emission tomography) scan. I sup...  Read Full »

Kindly view my liver biopsy report and explain.

Query: Hello doctor, Kindly tell me what is going on in my liver with my biopsy report.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the I have read your biopsy histopathology report (attachment removed to protect patient identity) and following is my explanation of the report. The human liver consist of portal tract, central vein and hepatocytes. Your biopsy report shows mild portal tract inflamm...  Read Full »

Are CAT scans with contrast more reliable than without contrast?

Query: Hi doctor, I had a CAT scan done two weeks ago with dye. It showed that my liver was normal. I had another one done yesterday as I am having problems with diverticulitis with dye and oral white drink. This one showed subtle roughness of liver, suggesting cirrhosis. I have had elevated liver enzym...  Read Full »

Dr. Divakara. P

Answer: Hi, Welcome to Your question is really genuine. Cirrhosis is a slowly evolving disease and it cannot occur in a matter of weeks. Hence, it is extremely unlikely that cirrhosis has happened in two weeks. In my opinion, either one of the scan report is interpreted wrongly. In my o...  Read Full »

How long will it take to cure my mother, who is suffering from Hepatitis C?

Query: Hi doctor, My mother is 59 years old, with type 2 diabetes for the past 15 years. She is taking medications for diabetes, blood pressure and multivitamin Centrum Her diabetes and BP are under control. Before four months, she had severe vomiting, fever and body pain. We approached a hospital and did ...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hi, Welcome to I went through your post and investigations (attachment removed to protect patient identity). Your mother is having hepatitis C, which if untreated can lead to liver failure and the treatment success rate is 95 to 99 %. The status of liver disease can be assessed by t...  Read Full »

Is it necessary to get an MRI for checking liver lesions in a patient with amyopathic dermatomyositis?

Query: Hi doctor, I was just diagnosed with amyopathic dermatomyositis, and I have been put through a lot of cancer screenings as this does not run in my family. All tests are normal, except regular ultrasound of the abdomen showed two non-specific liver lesions up to 3.2 cm. The previous CT scan of the a...  Read Full »

Dr. Sadaf Mustafa

Answer: Hello, Welcome to Usually, non-specific liver lesions are mentioned as hemangiomas. CT scan without contrast would not pick them that easily, they may have been present then. Even if hemangiomas were not there, they may have developed over time and are benign. Having said that, it is ...  Read Full »

What does steatohepatitis with perisinusoidal and periorbital fibrosis indicate?

Query: Hello doctor, Please interpret the liver biopsy report shown below. Kindly explain the what stage of fibrosis and confirm whether cirrhosis is present or not. Pathological diagnosis: A. Liver parenchyma biopsy: Steatohepatitis with perisinusoidal and periportal fibrosis. Note: The biopsy ...  Read Full »

Dr. Ujjawalkanti Ray

Answer: Hello, Welcome to The most common cause of periportal and perisinusoidal fibrosis with chronic inflammatory cell infiltration is due to steatohepatitis in both alcoholic and non-alcoholic. However, chances are very high in alcoholics. Periportal fibrosis can occur due to Schistosoma ...  Read Full »

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