Please help me understand the liver biopsy of a diabetic patient.

Question

Hello doctor,

Below is the biopsy report of my father who is 72-year-old diabetic. He was not feeling well for past one month. Can you please help me understand what does it mean? The liver biopsy result states that:

Gross: Linear cores of tissue largest measuring 1 cm-A/E (pJA/SH).
Microscopy: shows liver tissue with a neoplasm composed of cells arranged in nests and cords separated by sinusoids. Cells have pleomorphic nuclei with intranuclear inclusion, prominent nucleoli, and abundant eosinophilic cytoplasm.

Kindly help.

Answer 1

Hi,

Welcome to icliniq.com.

I am very afraid to tell you that these reports (attachment removed to protect patient identity) are suggestive of liver cancer. This needs to be evaluated by further CECT (contrast-enhanced computed tomography) abdomen and PET (positron emission tomography) scan. I suppose you should see a cancer specialist as soon as possible. I hope it helps you.

Thank you.

Answer 2

Hi,

Welcome back to icliniq.com.

It depends on the spread and primary focus of cancer. So, a PET scan followed by radiotherapy and chemotherapy would be required.

Thank you.