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Lyme disease is a vector-borne disease caused by bacteria, borrelia, and spread by blackleg ticks. It can produce various symptoms, including fever, rash (typically in the form of a pattern known as Bull's eye rash), joint discomforts, and headache. If left untreated, it can spread to other organ systems such as the brain, central nervous system, heart, cardiovascular system, and joints, causing difficulties. It is best to get diagnostic blood testing done. For example, the ELISA (enzyme-linked immunosorbent assay) test and a second test called the Western blot test may be used to confirm Lyme disease.
The CDC (Centers for Disease Control and Prevention) recommends a two-step testing approach for Lyme disease. If this initial stage is negative, no additional testing is required. However, if the first step is affirmative or uncertain (sometimes known as "equivocal"), it is recommended to take the second step. The overall result is only positive when the first and second tests are positive (or equivocal for some tests).
Most Lyme disease tests are designed to identify antibodies produced by the body in response to infection. Antibodies can take several weeks to form, so you may test negative if you were very recently infected. Antibodies typically remain in the blood for months or even years after the infection has resolved; hence, these tests cannot confirm a cure. Early action is therefore essential. Other blood tests may be conducted to detect any related abnormalities, including CBC (complete blood count), ESR (erythrocyte sedimentation rate), CRP (c-reactive protein), renal function tests, and so on. Early treatment with antibiotics such as Doxycycline, Amoxycillin, and Cefuroxime for around two weeks under the supervision of local infectious disease (ID) physicians helps avoid problems. However, the condition becomes highly resistant to therapy if various systemic complications develop. Even if you are asymptomatic, it is suggested to contact a local ID physician and have a diagnostic test, followed by treatment if positive.